@article{oai:nagoya.repo.nii.ac.jp:00016511,
 author = {YASUDA, KANAE},
 issue = {3},
 journal = {Nagoya Journal of Medical Science},
 month = {Dec},
 note = {The potential value of trimethylsilyl ethers has been reported in the field of gas chromatographic analysis of steroids. So far as has been known, satisfactory procedures affording trimethylsilyl ethers of corticosteroids have not been attained because of variable by-products produced but such a result was by no means incomprehensible. In the present study, an abbreviated procedure of trimethylsilylation, especially suited for use in this country, was devised and the determining conditions for conversion to the derivative was studied; required derivatives could be obtained by selecting proper conditions although satisfactory results could not be achieved for a series of naturally occurring steroids with polyfunctional groups. The steroid number data presented here, in agreement with the original view, substantiated the regularity and the significance of the steroid numbers for various derivatives of less polar steroids. It is of interest that the degree of irregularity in steroid number was generally related to the complexity of polar groups, the presence of reactive structures in a steroid molecule; so that steroids of corticoid type, being more polar, showed steroid numbers far from the expected values. probably due to the complicated side reaction during trimethylsilylation, on the one hand, and on the other, probably due to the interrelationship between reactive structures being much more extended than so called "vicinal effect" which has been pointed out in the gas chromatographic behaviour of polyfunctional steroids.},
 pages = {269--307},
 title = {Gas Chromatographic Analysis of Steroid Hormones : Part II. Gas Chromatographic Behaviour of Trimethylsilyl Ethers},
 volume = {30},
 year = {1967}
}