@article{oai:nagoya.repo.nii.ac.jp:00016514,
 author = {KUBO, MASAAKI},
 issue = {3},
 journal = {Nagoya Journal of Medical Science},
 month = {Dec},
 note = {The present study was undertaken to demonstrate, electron microscopically, a detailed localization of peroxidase and dopa·oxidase within the neutrophils of various maturities and further to correlate them with the development of cellular organelles and with the granulogenesis. The bone marrow of rats were used as materials. Perdxidase and dopa-oxidase reactions, as seen through an electron microscope, localize in the granules, and these two stainings show similar distributions throughout the various developing stages of the neutrophil. However, dopa-oxidase reaction never appear in Golgi region while peroxidase reaction stains either vesicles or cisternae in neutrophilie promyelocyte and myelocyte. These two reactions show a distinct difference in intensity and localization of stainings in the granules between the specific and nonspecific granules in neutrophil. Particularly, wtih the peroxidase reaction, a discrimination is possible between the Golgi vesicle maturing to specific grannule and that maturing to nonspecific one. The specific granules which do not stain with these two reactions appear for the first time in metamyelocyte and increase in number in more mature neutrophils.},
 pages = {327--340},
 title = {A Cytochemical Electron Microscopic Study of Glanulogenesis in Neutrophils Peroxidase and Dopa-Oxidase Reactions},
 volume = {30},
 year = {1967}
}