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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 31(1)

Studies on Nonprecipitating Insulin Antibody : Radioimmunoassay of Insulin Binding Capacity and Its Relationship to Insulin Neutralizing Activity and Ability to Evoke Cutaneous Anaphylactic Reaction

https://doi.org/10.18999/nagjms.31.1.143
https://doi.org/10.18999/nagjms.31.1.143
344c4689-b7f4-46e9-9260-2f9c9cd7194a
名前 / ファイル ライセンス アクション
v31n1p143_153.pdf v31n1p143_153.pdf (1.3 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-09-26
タイトル
タイトル Studies on Nonprecipitating Insulin Antibody : Radioimmunoassay of Insulin Binding Capacity and Its Relationship to Insulin Neutralizing Activity and Ability to Evoke Cutaneous Anaphylactic Reaction
著者 NAKAMURA, HIROO

× NAKAMURA, HIROO

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NAKAMURA, HIROO

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抄録
内容記述 Skom and Talmage have demonstrated a non-precipitating antibody against insulin in the sera of insulin-treated diabetics. But their method of determining the antibody is not quantitative. In the present study, a titration of the insulin binding activity of anti-insulin was performed more quantitatively using 131I-labeled insulin and antiguinea pig γ-globulin rabbit sera under the condition of insulin excess. Moreover, the insulin binding activity of anti-insulin was correlated with its insulin neutralizing activity and also with its ability to evoke a cutaneous anaphylactic reaction. A considerably good correlation was observed between the insulin neutralizing activity and insulin binding activity. On the other hand, between the insulin binding activity and the ability to evoke cutaneous anaphylactic reaction was only a poor correlation observed.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.31.1.143
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/311/311.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 31, 号 1, p. 143-153, 発行日 1968-06
著者版フラグ
値 publisher
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