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Studies on Nonprecipitating Insulin Antibody : Radioimmunoassay of Insulin Binding Capacity and Its Relationship to Insulin Neutralizing Activity and Ability to Evoke Cutaneous Anaphylactic Reaction
https://doi.org/10.18999/nagjms.31.1.143
https://doi.org/10.18999/nagjms.31.1.143344c4689-b7f4-46e9-9260-2f9c9cd7194a
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-09-26 | |||||
タイトル | ||||||
タイトル | Studies on Nonprecipitating Insulin Antibody : Radioimmunoassay of Insulin Binding Capacity and Its Relationship to Insulin Neutralizing Activity and Ability to Evoke Cutaneous Anaphylactic Reaction | |||||
著者 |
NAKAMURA, HIROO
× NAKAMURA, HIROO |
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抄録 | ||||||
内容記述 | Skom and Talmage have demonstrated a non-precipitating antibody against insulin in the sera of insulin-treated diabetics. But their method of determining the antibody is not quantitative. In the present study, a titration of the insulin binding activity of anti-insulin was performed more quantitatively using 131I-labeled insulin and antiguinea pig γ-globulin rabbit sera under the condition of insulin excess. Moreover, the insulin binding activity of anti-insulin was correlated with its insulin neutralizing activity and also with its ability to evoke a cutaneous anaphylactic reaction. A considerably good correlation was observed between the insulin neutralizing activity and insulin binding activity. On the other hand, between the insulin binding activity and the ability to evoke cutaneous anaphylactic reaction was only a poor correlation observed. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.31.1.143 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/311/311.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 31, 号 1, p. 143-153, 発行日 1968-06 |
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著者版フラグ | ||||||
値 | publisher |