@article{oai:nagoya.repo.nii.ac.jp:00016532, author = {KAMIYA, TAKESHI}, issue = {2}, journal = {Nagoya Journal of Medical Science}, month = {Sep}, note = {The present study concerns with the vascular changes of the spinal cord, when it is compressed anteriorly such as spondylotic myelopathy. The method of spinal cord compression was explored to give the pressure only anteriorly without opening the spinal canal. The procedure is to approach anteriorly to the vertebral column and the intervertebral disc is drilled and the anterior aspect of the spinal cord is visualized without the laminectomy procedure which may act as a decompressive. Microangiographic study is made with extensive injection of aqueous suspension of micro-particle of barium sulfate into arterial system of the spinal cord via the vertebral arteries. Various sections of less than 5 mm in thickness are made of the spinal cord in which the arterial system has been filled with barium. Transverse section of the spinal cord readily shows the beautiful pattern of arterial supply on the microangiogram. Parasagittal section of the spinal cord, however, is found best to demonstrate the change of vascular pattern in the case of anterior cord compression. From the present observations, the results are summarized as follows: 1. The anterior spinal artery is difficult to be occluded by anterior pressure, so that the theories of anterior spinal artery insufficiency in the case of spondylotic myelopathy seem equivocal. 2. Parasagittal sections show early and persistent change of the central arteries by anterior pressure instead. 3. Deformity of the spinal cord could be due to tight fixation by the dentate ligaments, and this deformity could be the main cause of the central artery insufficiency. Vascular changes of the spinal cord by anterior pressure were discussed in detail in regard to the pathogenesis of spondylotic myelopathy.}, pages = {171--190}, title = {Experimental Study on Anterior Spinal Cord Compression with Special Emphasis on Vascular Disturbance}, volume = {31}, year = {1968} }