@article{oai:nagoya.repo.nii.ac.jp:00016533, author = {WATANABE, SABURO}, issue = {2}, journal = {Nagoya Journal of Medical Science}, month = {Sep}, note = {This report is to shew the basic study-histological follow up-of my "cyanoacrylate monomer adhesive-polyfion coated tetoron mesh technique" which was advocated and applied in our neurosurgical practice for past 6 years in over 100 clinical cases. This technique was adapted for clinical application with fairly brief experimental works at begining, since it was known these materials were not noxious and the amount of application was so little. This technique is useful especially in neurosurgical operation such as dura substitute transplantation in the cases of head injury, complete removal of dura infiltrating brain tumors, repair of cerebrospinal fluid leakage, repair of big dural venous sinuses and wrapping procedure of intracranial aneurysms. For the experimental investigations, 50 mongrel adult dogs were used as experimental animals. The tetoron mesh was transplanted to patch the experimentally produced dural deficit and broken dural venous sinus. Grossly, this technique seems to be satisfactory for the repair of these. Histological study of the grafts, taken after 10-180 post-operative days, reveals gradual absorption of cyanoacrylate glue and apparently the glue was phagocytosed and emigrated away as the intracellular deposit of giant cells. As the matters of fact, many cases showed no evidence or even a trace of this glue in careful dissection. Healing process of grafted region is made without excess granulomatous tissue, but proper formation of neomembrane over the graft. Conclusively, this technique seems more preferable than any other reported procedures.}, pages = {191--205}, title = {Application of Tetoron Mesh-Adhesive Technique in Neurosurgery}, volume = {31}, year = {1968} }