@article{oai:nagoya.repo.nii.ac.jp:00016588, author = {HAYAKAWA, TETSUO}, issue = {2}, journal = {Nagoya Journal of Medical Science}, month = {Jan}, note = {Studies were made on the methods for urinary amylase determination, stability of the enzyme, isoamylase in urine, normal ranges, diagnostic value in various diseases (pancreatic and non-pancreatic), and relationship between urinary amylase excretion and other laboratory tests. The saccharogenic method of Somogyi was chosen after comparing the three methods of Somogyi, Wohlgemuth, and Van Loon. Somogyi method was modified and simplified to be used for a screening test of pancreatic diseases. Diagnostic values of urinary amylase were evaluated in 54 control subjects, in 73 patients with pancreatic disease, and in 51 with non- pancreatic disease using this simplified method. Urinary amylase excretion was found to be a more sensitive and reliable index than amylase concentration in serum or urine for the diagnosis of acute pancreatitis, also of chronic pancreatitis and of carcinoma. The amylase excretion well reflected the clinical course of pancreatitis and served as a good indicator of its convalescent care. Differential diagnosis may be facilitated by determining urinary amylase excretion in the diseases which have elevated amylase values.}, pages = {185--214}, title = {Clinical Significance of Urinary Amylase in Diagnosis of Pancreatic Disease}, volume = {32}, year = {1970} }