{"created":"2021-03-01T06:23:52.390729+00:00","id":16603,"links":{},"metadata":{"_buckets":{"deposit":"0e710eb0-68fd-4a99-bec8-e79895b2e8df"},"_deposit":{"created_by":17,"id":"16603","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"16603"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00016603","sets":["499:508:509:1515"]},"author_link":["98582"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1970-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"451","bibliographicPageStart":"445","bibliographicVolumeNumber":"32","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Effects of palmitic acid, inhibitors, uncouplers, and reduced and oxidized glutathione on the binding of insulin^-131I and 131I to the isolated fresh or aged mitochondria were studied. The binding of insulin^-1311 to the fresh mitochondria was unexpectedly increased to a greater degree with the exogenous addition of palmitic acid, glutathione, acetaldehyde and 2,4-dinitrophenol to the medium. The fact indicated that the intactness of mitochondria was not prerequisite for the binding of insulin^-131I to the isolated mitochondria. The binding of insulin^-131I was compared to the fresh mitochondria and the aged mitochondria. Insulin^-131[ bouud to the aged mitochondria in a lesser degree. It is suggested that the binding of insulin^-131I to the mitochondria might be related to the mitochondrial functional and conformational state. The binding of 131I to the mitochondria was apparently differrnt from that of insulin^-131I. And the binding of 131I was not altered by these uncouplers except in the case of acetaldehyde and ethyl alcohol. This implies that the process of binding of insulin^-131I is different from that of 131I. In the case of 131I, it may have some connections with its ion transport mechanism.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.32.3-4.445","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KATSUMATA, KAZUO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"98582","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"v32n34p445_451.pdf","filesize":[{"value":"783.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"v32n34p445_451.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/16603/files/v32n34p445_451.pdf"},"version_id":"3cbe533e-8e4f-431d-babd-f5169f68636e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of Palmitic Acid on the Binding of Insulin^-131I to the Rat Liver Mitochondria","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Palmitic Acid on the Binding of Insulin^-131I to the Rat Liver Mitochondria","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1515"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-10-04"},"publish_date":"2013-10-04","publish_status":"0","recid":"16603","relation_version_is_last":true,"title":["Effects of Palmitic Acid on the Binding of Insulin^-131I to the Rat Liver Mitochondria"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T05:29:37.412072+00:00"}