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Colorimetric Estimation of Succinic Dehydrogenase Activity by Neotetrazolium Chloride as a Tumor Sensitivity Test to Chemotherapeutic Agents
https://doi.org/10.18999/nagjms.33.3.247
https://doi.org/10.18999/nagjms.33.3.2479273ed50-f1d6-4ce9-aeac-f9e1c23ba0ce
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-10-09 | |||||
タイトル | ||||||
タイトル | Colorimetric Estimation of Succinic Dehydrogenase Activity by Neotetrazolium Chloride as a Tumor Sensitivity Test to Chemotherapeutic Agents | |||||
言語 | en | |||||
著者 |
ICHIHASHI, HIDEHITO
× ICHIHASHI, HIDEHITO× SASAKI, SUSUMU× KONDO, TATSUHEI |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
抄録 | ||||||
内容記述 | In the search for tumor sensitivity test to chemotherapeutic agents succinic dehydrogenase activity by neotetrazolium chloride was measured colorimetrically. The rate of formazan production was proportional to the amount of Ehrlich ascites tumor cells, accelerated by the addition of ascorbic acid, and inhibited by the addition of iodoacetic acid. The inhibitory rate of formazan production of tumor cells treated with chemotherapeutic agents was well correlated with the survival time of mice. Of the chemotherapeutic agents, mitomycin C was the most effective, either singly or in combination with other drugs. Considering the mechanisms of action of drug and of the host's defense, an in vivo tumor system was studied as a screening test for the chemotherapeutic agents. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.33.3.247 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/333/333.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 33, 号 3, p. 247-256, 発行日 1971-02 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/18673 | |||||
識別子タイプ | HDL |