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Suppression of Cell-Mediated Immunity Through Immune Spleen Cells Against Ehrlich Ascites Tumor
https://doi.org/10.18999/nagjms.33.4.329
https://doi.org/10.18999/nagjms.33.4.329d48bf039-f596-4f83-8e55-38aa9855f7dd
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-10-09 | |||||
タイトル | ||||||
タイトル | Suppression of Cell-Mediated Immunity Through Immune Spleen Cells Against Ehrlich Ascites Tumor | |||||
著者 |
OKUBO, SHINJI
× OKUBO, SHINJI |
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抄録 | ||||||
内容記述 | The adoptive transfer of immunity to Ehrlich ascites tumor was accomplished during the first two weeks in a syngeneic murine system by the intraperitoneal administration of spleen cells obtained from mice which had been hyperimmunized through three subcutaneous inoculations with the tumor. The resistance induced in this system was noted duing first two weeks after tumor challenge, and thereafter there was an increased tendency for the tumor to become enhanced. Serum from mice which had previously contacted with Ehrlich ascites tumor showed enhancing effect on the subcutaneous growth of the tumor to a certain degree. Anti-tumor effect of spleen cells from various donors was examined by a simple method involving intraperitoneal injection of tumor cells and spleen cells which had been mixed and incubated for a short period of time. The results seem to indicate that suppression of tumor growth was induced by cell-mediated immunity through injected immune spleen cells, and that enhancement of tumor growth depended basically upon the ability of humoral antibodies which apparently had been produced through transferred spleen cells to suppress the development of cell-mediated immune response. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.33.4.329 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 33, 号 4, p. 329-340, 発行日 1971-03 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/334/334.html | |||||
識別子タイプ | URI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/18679 | |||||
識別子タイプ | HDL |