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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 33(4)

Suppression of Cell-Mediated Immunity Through Immune Spleen Cells Against Ehrlich Ascites Tumor

https://doi.org/10.18999/nagjms.33.4.329
https://doi.org/10.18999/nagjms.33.4.329
d48bf039-f596-4f83-8e55-38aa9855f7dd
名前 / ファイル ライセンス アクション
v33n4p329_340.pdf v33n4p329_340.pdf (1.4 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-10-09
タイトル
タイトル Suppression of Cell-Mediated Immunity Through Immune Spleen Cells Against Ehrlich Ascites Tumor
著者 OKUBO, SHINJI

× OKUBO, SHINJI

WEKO 49556

OKUBO, SHINJI

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抄録
内容記述 The adoptive transfer of immunity to Ehrlich ascites tumor was accomplished during the first two weeks in a syngeneic murine system by the intraperitoneal administration of spleen cells obtained from mice which had been hyperimmunized through three subcutaneous inoculations with the tumor. The resistance induced in this system was noted duing first two weeks after tumor challenge, and thereafter there was an increased tendency for the tumor to become enhanced. Serum from mice which had previously contacted with Ehrlich ascites tumor showed enhancing effect on the subcutaneous growth of the tumor to a certain degree. Anti-tumor effect of spleen cells from various donors was examined by a simple method involving intraperitoneal injection of tumor cells and spleen cells which had been mixed and incubated for a short period of time. The results seem to indicate that suppression of tumor growth was induced by cell-mediated immunity through injected immune spleen cells, and that enhancement of tumor growth depended basically upon the ability of humoral antibodies which apparently had been produced through transferred spleen cells to suppress the development of cell-mediated immune response.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.33.4.329
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 33, 号 4, p. 329-340, 発行日 1971-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/334/334.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/18679
識別子タイプ HDL
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