@article{oai:nagoya.repo.nii.ac.jp:00016639,
 author = {URUSHIBATA, KIYOSHI},
 issue = {1},
 journal = {Nagoya Journal of Medical Science},
 month = {Jun},
 note = {Adrenocortical tumors or adrenal glands, obtained from cases of Cushing's syndrome consisting of two cases of adrenocortical cancer, three of adrenocortical adenoma, five of adrenocortical hyperplasia and two of adrenocortical nodular hyperplasia were studied by electron microscopy and compared with normal glands. Nodular hyperplasia was differentiated from simple hyperplasia by the unique clinical and fine structural features. The fine structure of adrenocortical cancer cells, which has not been reported up to the present, revealed well developed microvilli and Golgi complex, circular cristae and intramitochondrial body and two kinds of unidentified microbodies in the cytoplasma. Mitochondria of adenoma cells exhibited various sizes and round or oval shape displaying tubulo-vesicular cristae. Smooth surfaced endoplasmic reticulum (s.E.R.) was relatively well developed in many cases of Cushing's syndrome. Rough surfaced endoplasmic reticulum (r.E.R.) was well developed in the case of adenoma, especially in an infant case. Normal lipid droplets were sparse in cases of adenoma and nodular hyperplasia, but small round and homogenous dense bodies were observed in these two groups, especially abundantly in the latter. The fine structure of simple adrenocortical hyperplasia was almost similar to normal adrenal cortex except for the existence of many intramitochondrial bodies. The fine structural characteristics of adrenocortical tumor or adrenal cortex in Cushing's syndrome were a well developed s.E.R., variety in the size of mitochondria, various cristae of mitochondria and prominent Golgi complex.},
 pages = {27--39},
 title = {Fine Structure of Adrenocortical Cell in Cushings's Syndrome},
 volume = {34},
 year = {1971}
}