@article{oai:nagoya.repo.nii.ac.jp:00016655, author = {KOBAYASHI, HISANDO and TAUCHI, HISASHI}, issue = {3}, journal = {Nagoya Journal of Medical Science}, month = {Feb}, note = {Histological, histochemical, biochemical and electron microscopic studies were performed on the liver of an autopsy case of drug-induced lipidosis. The important electron microscopic findings were numerous myelin figures and aggregates of fibrils network in the hepatic cells. It was noted that the fibrils in aggregates of network structure communicated with the myelin figures. The appearance of the changes could be dosely related to the mitochondria. The electron microscopic specimens immersed in digitonin solution showed that free cholesterol excessively accumulated in the hepatic cells, and also appeared in the myelin figures and aggregates of fibrils network as one of the chemical composition. Histochemical examination of the liver, spleen, lymph~odes.and bone marrow indicated the phospholipid deposition in general organs.}, pages = {259--266}, title = {Ultrastructural Demonstration of Excessively Accumulated free Cholesterol in the Hepatic Cells in a Case of So-Called Phospholipidosis}, volume = {34}, year = {1972} }