@article{oai:nagoya.repo.nii.ac.jp:00016699,
 author = {KOBAYASHI, HISANDO and HOSINO, MUNEMITSU and TAUCHI, HISASHI},
 issue = {1},
 journal = {Nagoya Journal of Medical Science},
 month = {Aug},
 note = {Light, electron microscopic, enzyme histochemical and ultracytochemical studies were performed on specimens of oncocytoma, obtained from an asymptomatic mass in the right parotid gland of a 61 year old Japanese female. With the light microscope, the diagnosis was benign oncocytoma. Electron microscopically, the cytoplasm was filled with a vast number of mitochondria, with numerous cristae, some of which contained glycogen particles. The tumor cells showed a strong activity of histochemically demonstrable cytochrome oxidase. At ultrastructural level for the demonstration of cytochrome oxidase, using DAB, many of the mitochondria had reaction product, which was restricted only to the cristae and the intracristal space. Also, the glycogen-containing-mitochondria had the enzyme activity on the cristae and in the intracristal space. The mitochondria of oncocytes could have considerably active function. These results suggest that oncocytoma which is characterized by numerous mitochondria could be in hyperactive function rather than degeneration.},
 pages = {25--32},
 title = {Ultrastructural Study of Cytochrome Oxidase in Oncocytoma},
 volume = {35},
 year = {1972}
}