{"created":"2021-03-01T06:23:58.963907+00:00","id":16703,"links":{},"metadata":{"_buckets":{"deposit":"8844b289-9d04-4fb4-9073-6507c1d19900"},"_deposit":{"created_by":17,"id":"16703","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"16703"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00016703","sets":["499:508:509:1528"]},"author_link":["98636","98637"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1973-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-4","bibliographicPageEnd":"77","bibliographicPageStart":"69","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"1. The effect of tolbutamide on the oxidation rate, respiratory control index and P/0 ratio of intact rat liver mitochondria was studied. 2. Addition of more than 30 mg% tolbutamide apparently increased the state 4 respiration rate and decreased RCI, whereas, 80 mg% tolbutamide decreased markedly the state 3 respiration rate than that of control. State 4 respiration rate was accelerated by adding 100 mg% (3.8 mM) tolbutamide, while state 3 respiration rate was decreased and P/ 0 ratio was reduced to zero showing complete uncoupling. 3. Uncoupling of oxidative phosphorylation by 100 mg% tolbutamide was similar to that of DNP, i.e., sensitive to the addition of rutamyin, 100 mg% tolbutamide can induce ATPase activity of intact rat liver mitochondria, and induced A TPase activity was reduced to zero by the addition of rutamyin just like DNP. Therefore, uncoupling site by tolbutamide may be close to the DNP sensitive site.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.35.2-4.69","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/3524/3524.html","subitem_relation_type_select":"URI"}}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KATSUMATA, KAZUO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"98636","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HAGIHARA, MASAKO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"98637","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"v35n24p69_77.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"v35n24p69_77.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/16703/files/v35n24p69_77.pdf"},"version_id":"6c8331aa-8763-4179-a837-11a19c30e5cb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Uncoupling Effect of Tolbutamide on Oxidative Phosphorylation of Liver Mitochondria","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Uncoupling Effect of Tolbutamide on Oxidative Phosphorylation of Liver Mitochondria","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1528"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-10-17"},"publish_date":"2013-10-17","publish_status":"0","recid":"16703","relation_version_is_last":true,"title":["Uncoupling Effect of Tolbutamide on Oxidative Phosphorylation of Liver Mitochondria"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T05:31:28.038684+00:00"}