@article{oai:nagoya.repo.nii.ac.jp:00016705, author = {KATSUMATA, KAZUO}, issue = {2-4}, journal = {Nagoya Journal of Medical Science}, month = {Mar}, note = {The effect of thiamine and its various derivatives on the respiratory control of rat liver mitochondria was examined. Except TDP all other thiamine derivatives tested were shown to damage mitochondrial respiration. In these experiments DCET and TATD are shown to be strong inhibitors. It was noted that thiamine and its derivatives except TDP have aldehyde group in their chemical structure. Because formaldehyde and acetalhyde are inhibitors to the respiration of the isolated rat liver mitochondria, the aldehyde group in chemical structure is speculated to have some relation to their action on liver mitochondria. Further studies are necessary concerning the mechanism of the inhibitory actions of thiamine derivatives.}, pages = {85--90}, title = {The Effect of VB1 and its Derivatives on the Respiration of the Isolated Rat Liver Mitochondria}, volume = {35}, year = {1973} }