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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 76(1-2)

External Beam Radiotherapy for Painful Bone Metastases from Hepatocellular Carcinoma: Multiple Fractions Compared with an 8-Gy Single Fraction

https://doi.org/10.18999/nagjms.76.1-2.91
https://doi.org/10.18999/nagjms.76.1-2.91
4c945fe8-cd5f-4031-9ff5-28d89f8866da
名前 / ファイル ライセンス アクション
10_Hayashi.pdf 10_Hayashi.pdf (172.0 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2014-03-04
タイトル
タイトル External Beam Radiotherapy for Painful Bone Metastases from Hepatocellular Carcinoma: Multiple Fractions Compared with an 8-Gy Single Fraction
著者 HAYASHI, SHINYA

× HAYASHI, SHINYA

WEKO 51141

HAYASHI, SHINYA

Search repository
TANAKA, HIDEKAZU

× TANAKA, HIDEKAZU

WEKO 51142

TANAKA, HIDEKAZU

Search repository
HOSHI, HIROAKI

× HOSHI, HIROAKI

WEKO 51143

HOSHI, HIROAKI

Search repository
キーワード
主題Scheme Other
主題 Hepatocellular carcinoma
キーワード
主題Scheme Other
主題 Bone metastases
キーワード
主題Scheme Other
主題 Palliative therapy
キーワード
主題Scheme Other
主題 Radiotherapy
キーワード
主題Scheme Other
主題 Dose–response relationship
抄録
内容記述 External beam radiotherapy (EBRT) for hepatocellular carcinoma (HCC) bone metastases has not been popular in palliative therapy, and optimum dose schedules have not been decided because of limited published reports. We here evaluated the palliative effect of EBRT for HCC bone metastases and compared the dose–response relationship between multiple fractions (MFs) and an 8-Gy single fraction (SF). Twenty-eight patients (42 sites) with painful bone metastases who received EBRT and were analyzed retrospectively. Eight patients (12 sites) received SF. Of the remaining 20 patients (30 sites), 10 received MFs at moderate doses (20–30 Gy; 17 sites) and 10 received MFs at high doses (36–52 Gy; 13 sites). Overall response was achieved at 83% (35) of all sites; 75% (9) and 87% (26) for the SF and MF patients (88%, moderate dose; 85%, high dose), respectively. No significant differences in overall response were observed between each fraction schedule. Response duration was significantly longer for the high-dose MF patients than for the SF patients and moderate-dose MF patients (P < 0.05). SF was as effective as MF radiotherapy in terms of pain relief, but high-dose MF delivery relieved pain for a significantly longer duration.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.76.1-2.91
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 76, 号 1-2, p. 91-99, 発行日 2014-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7612/7612.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/19487
識別子タイプ HDL
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