{"created":"2021-03-01T06:25:36.685434+00:00","id":18216,"links":{},"metadata":{"_buckets":{"deposit":"49a144e6-4690-42d4-a97d-903d2cf3d69a"},"_deposit":{"created_by":17,"id":"18216","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"18216"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00018216","sets":["1213:1620:1621:1623"]},"author_link":["53122","53123","53124","53125","53126","53127","53128","53129","53130","53131","53132","53133","53134","53135"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_alternative_title_19":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Effects of allopurinol on insulin action in fructose-fed rats","subitem_alternative_title_language":"en"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-03-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"27","bibliographicPageStart":"23","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"総合保健体育科学","bibliographic_titleLang":"ja"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: To investigate how allopurinol (a xanthine oxidase inhibitor) improves insulin action of rats fed with high-fructose diet. Methods: Male Wistar rats were randomly divided into 3 groups and each group was fed one of the following diets for 4 weeks: standard chow diet, high-fructose diet, and high-fructose diet plus allopurinol. A part of rats in the high-fructose diet plus allopurinol group were infused with a NOS inhibitor, NG-monomethyl-Larginine (L-NMMA), during the euglycemic clamp studies (insulin infusion rate: 3.0mU/kg/min). Insulin sensitivity index was assessed from the oral glucose tolerance test (OGTT). Results: Serum uric acid and plasma insulin concentrations were significantly decreased with allopurinol treatment. High-fructose feeding produced a marked decrease in insulin sensitivity index compared with standard chow diet feeding. Allopurinol treated high-fructose fed rats showed a significant increase in insulin sensitivity index, reaching a similar level as that of the standard chow diet feeding. Infusion of L-NMMA did not change the glucose infusion rate of high-fructose fed rats with allopurinol in the euglycemic clamp. Conclusion: Improvement of insulin action with allopurinol in fructose-fed rats may not be associated with increase in production of nitric oxide.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/20222"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/njhpfs.35.1.23","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"名古屋大学総合保健体育科学センター","subitem_publisher_language":"ja"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0289-5412","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"姜, 海英","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"53122","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小池, 晃彦","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"53123","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"木, 蘭","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"53124","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"夏目, 有紀枝","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"53125","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"王, 忠華","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"53126","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"成, 憲武","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"53127","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"押田, 芳治","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"53128","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Jiang, Haiying","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53129","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koike, Teruhiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53130","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mu, Lan","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53131","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Natsume, Yukie","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53132","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wang, Zhonghua","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53133","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Cheng, Xianwu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53134","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oshida, Yoshiharu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53135","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-21"}],"displaytype":"detail","filename":"4_No35-1.pdf","filesize":[{"value":"940.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"4_No35-1.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/18216/files/4_No35-1.pdf"},"version_id":"d6c59811-2121-4a6f-ab35-c8c90e07f7e8"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"高果糖食負荷ラットでのインスリン作用に対するアロプリノールの影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"高果糖食負荷ラットでのインスリン作用に対するアロプリノールの影響","subitem_title_language":"ja"}]},"item_type_id":"9","owner":"17","path":["1623"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-06-11"},"publish_date":"2014-06-11","publish_status":"0","recid":"18216","relation_version_is_last":true,"title":["高果糖食負荷ラットでのインスリン作用に対するアロプリノールの影響"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-21T02:19:14.652352+00:00"}