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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 76(3-4)

CARDIAC COUNTERCLOCKWISE ROTATION IS A RISK FACTOR FOR HIGH-DOSE IRRADIATION TO THE LEFT ANTERIOR DESCENDING CORONARY ARTERY IN PATIENTS WITH LEFT-SIDED BREAST CANCER WHO RECEIVING ADJUVANT RADIOTHERAPY AFTER BREAST-CONSERVING SURGERY

https://doi.org/10.18999/nagjms.76.3-4.265
https://doi.org/10.18999/nagjms.76.3-4.265
3ea646ad-3a6a-4b5c-a52f-369f81a13e8a
名前 / ファイル ライセンス アクション
05_Tanaka.pdf 05_Tanaka.pdf (3.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2014-09-05
タイトル
タイトル CARDIAC COUNTERCLOCKWISE ROTATION IS A RISK FACTOR FOR HIGH-DOSE IRRADIATION TO THE LEFT ANTERIOR DESCENDING CORONARY ARTERY IN PATIENTS WITH LEFT-SIDED BREAST CANCER WHO RECEIVING ADJUVANT RADIOTHERAPY AFTER BREAST-CONSERVING SURGERY
著者 TANAKA, HIDEKAZU

× TANAKA, HIDEKAZU

WEKO 53534

TANAKA, HIDEKAZU

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HAYASHI, SHINYA

× HAYASHI, SHINYA

WEKO 53535

HAYASHI, SHINYA

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HOSHI, HIROAKI

× HOSHI, HIROAKI

WEKO 53536

HOSHI, HIROAKI

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キーワード
主題Scheme Other
主題 breast cancer
キーワード
主題Scheme Other
主題 breast-conserving surgery
キーワード
主題Scheme Other
主題 breast radiotherapy
キーワード
主題Scheme Other
主題 cardiac toxicity
キーワード
主題Scheme Other
主題 coronary artery
抄録
内容記述 Patients irradiated for left-sided breast cancer have higher incidence of cardiovascular disease than those receiving irradiation for right-sided breast cancer. Most abnormalities were in the left anterior descending (LAD) coronary artery territory. We analyzed the relationships between preoperative examination results and irradiation dose to the LAD artery in patients with left-sided breast cancer. Seventy-one patients receiving breast radiotherapy were analyzed. The heart may rotate around longitudinal axis, showing either clockwise or counterclockwise rotation (CCWR). On electrocardiography, the transition zone (TZ) was judged in precordial leads. CCWR was considered to be present if TZ was at or to the right of V3. The prescribed dose was 50 Gy in 25 fractions. The maximum (Dmax) and mean (Dmean) doses to the LAD artery and the volumes of the LAD artery receiving at least 20 Gy, 30 Gy and 40 Gy (V20Gy, V30Gy and V40Gy, respectively) were significantly higher in CCWR than in the non-CCWR patients. On multivariate analysis, TZ was significantly associated with Dmax, Dmean, V20Gy, V30Gy, and V40Gy. CCWR is a risk factor for high-dose irradiation to the LAD artery. Electrocardiography is useful for evaluating the cardiovascular risk of high-dose irradiation to the LAD artery.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.76.3-4.265
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 76, 号 3-4, p. 265-272, 発行日 2014-08
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7634/7634.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/20545
識別子タイプ HDL
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