{"created":"2021-03-01T06:25:50.918674+00:00","id":18439,"links":{},"metadata":{"_buckets":{"deposit":"28ec67b7-82da-4036-bbe1-70c8cf640ee0"},"_deposit":{"created_by":17,"id":"18439","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"18439"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00018439","sets":["499:508:509:1637"]},"author_link":["53611","53612","53613","53614","53615","53616","53617","53618","53619","53620","53621","53622"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"368","bibliographicPageStart":"361","bibliographicVolumeNumber":"76","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Central nervous system (CNS) manifestations are rare complications of relapsing polychondritis (RP). The majority of patients respond well to glucocorticoid therapy, but need to maintain it. Some patients are refractory to initial glucocorticoid therapy and to additional immunosuppressants, and end up with an outcome worse than at therapy initiation. The standardized therapeutic protocol for this condition has not been established. The effects of anti-tumor necrosis factor (TNF) -α agents have been reported recently. We experienced a patient with RP and limbic encephalitis who was refractory to initial high-dose glucocorticoid, but subsequently responded to infliximab and did not show deterioration of signs and symptoms after stopping therapy. We report this case together with a systematic literature review. This is the first case report of RP with CNS manifestations successfully treated by an anti-TNF-α agent without recurrence after discontinuation.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/20556"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.76.3-4.361","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of 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NORIYUKI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53616","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SUZUKI, TOMIO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53617","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SATO, JUICHI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53618","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ATSUTA, NAOKI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53619","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SOBUE, GEN","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53620","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TAKAHASHI, YUKITOSHI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53621","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"BAN, NOBUTARO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"53622","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-21"}],"displaytype":"detail","filename":"23_Kondo.pdf","filesize":[{"value":"8.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"23_Kondo.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/18439/files/23_Kondo.pdf"},"version_id":"7e59b9cc-d507-4495-b90d-3e5b8d9cf435"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"relapsing polychondritis","subitem_subject_scheme":"Other"},{"subitem_subject":"limbic encephalitis","subitem_subject_scheme":"Other"},{"subitem_subject":"infliximab","subitem_subject_scheme":"Other"},{"subitem_subject":"anti-tumor necrosis factor-alpha agent","subitem_subject_scheme":"Other"},{"subitem_subject":"therapy discontinuation","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"LIMBIC ENCEPHALITIS ASSOCIATED WITH RELAPSING POLYCHONDRITIS RESPONDED TO INFLIXIMAB AND MAINTAINED ITS CONDITION WITHOUT RECURRENCE AFTER DISCONTINUATION : A CASE REPORT AND REVIEW OF THE LITERATURE","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"LIMBIC ENCEPHALITIS ASSOCIATED WITH RELAPSING POLYCHONDRITIS RESPONDED TO INFLIXIMAB AND MAINTAINED ITS CONDITION WITHOUT RECURRENCE AFTER DISCONTINUATION : A CASE REPORT AND REVIEW OF THE LITERATURE","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1637"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-09-08"},"publish_date":"2014-09-08","publish_status":"0","recid":"18439","relation_version_is_last":true,"title":["LIMBIC ENCEPHALITIS ASSOCIATED WITH RELAPSING POLYCHONDRITIS RESPONDED TO INFLIXIMAB AND MAINTAINED ITS CONDITION WITHOUT RECURRENCE AFTER DISCONTINUATION : A CASE REPORT AND REVIEW OF THE LITERATURE"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T05:20:44.831190+00:00"}