@article{oai:nagoya.repo.nii.ac.jp:00018455,
 author = {Ishikawa, Akira},
 issue = {4},
 journal = {Journal of Heredity},
 month = {Mar},
 note = {The genetic basis of heterosis has not been elucidated. Previously, a congenic mouse strain with a 44-Mb genomic region of proximal chromosome 2 containing the allele derived from wild Mus musculus castaneus at Pbwg1, a quantitative trait locus (QTL) for body weight and growth, has been developed. In this study, to fine-map and characterize body weight QTLs on the congenic region, QTL analysis of body weight at 1, 3, 6, and 10 weeks after birth was performed on a population of 265 F2 intercross mice between the developed congenic strain and its background strain C57BL/6J. A significant QTL (named Pbwg1.10) affecting body weight at 6 and 10 weeks of age was identified within an approximately 21-Mb support interval. Surprisingly, Pbwg1.10 had an overdominance effect and caused heterosis for body weight. This result supported the overdominance hypothesis explaining heterosis.},
 pages = {501--504},
 title = {Mapping an Overdominant Quantitative Trait Locus for Heterosis of Body Weight in Mice},
 volume = {100},
 year = {2009}
}