{"created":"2021-03-01T06:25:56.863258+00:00","id":18530,"links":{},"metadata":{"_buckets":{"deposit":"2661e8a6-99ca-44fb-8e2d-37d3b2baba76"},"_deposit":{"id":"18530","owners":[],"pid":{"revision_id":0,"type":"depid","value":"18530"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00018530"},"item_10_biblio_info_6":{"attribute_name":"\u66f8\u8a8c\u60c5\u5831","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"506","bibliographicPageStart":"500","bibliographicVolumeNumber":"369","bibliographic_titles":[{"bibliographic_title":"Biochemical and Biophysical Research Communications"}]}]},"item_10_description_4":{"attribute_name":"\u6284\u9332","attribute_value_mlt":[{"subitem_description":"De novo prediction of protein structures, the prediction of structures from amino acid sequences which are not similar to those of hitherto resolved structures, has been one of the major challenges in molecular biophysics. In this paper, we develop a new method of de novo prediction, which combines the fragment assembly method and the simulation of physical folding process: structures which have consistently assembled fragments are dynamically searched by Langevin molecular dynamics of conformational change. The benchmarking test shows that the prediction is improved when the candidate structures are cross-checked by an empirically derived score function.","subitem_description_type":"Abstract"}]},"item_10_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"http://dx.doi.org/10.1016/j.bbrc.2008.02.048"},{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/20616"}]},"item_10_publisher_32":{"attribute_name":"\u51fa\u7248\u8005","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_10_rights_12":{"attribute_name":"\u6a29\u5229","attribute_value_mlt":[{"subitem_rights":"This is the author's version of a work that was accepted for publication in Biochemical and Biophysical Research Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms, may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Biochemical and Biophysical Research Communications. v.369, n.2, 2008, p.500\u2013506, DOI: 10.1016/j.bbrc.2008.02.048"}]},"item_10_select_15":{"attribute_name":"\u8457\u8005\u7248\u30d5\u30e9\u30b0","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0006-291X","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"\u8457\u8005","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sasaki, Takeshi N."}],"nameIdentifiers":[{"nameIdentifier":"53829","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Cetin, Hikmet"}],"nameIdentifiers":[{"nameIdentifier":"53830","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sasai, Masaki"}],"nameIdentifiers":[{"nameIdentifier":"53831","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"\u30d5\u30a1\u30a4\u30eb\u60c5\u5831","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-21"}],"displaytype":"detail","filename":"SasakiCetinSasaiBBRC2008.pdf","filesize":[{"value":"541.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"SasakiCetinSasaiBBRC2008.pdf","url":"https://nagoya.repo.nii.ac.jp/record/18530/files/SasakiCetinSasaiBBRC2008.pdf"},"version_id":"c8c49ca6-5680-4206-be28-f57af38d1ee1"}]},"item_keyword":{"attribute_name":"\u30ad\u30fc\u30ef\u30fc\u30c9","attribute_value_mlt":[{"subitem_subject":"Protein structure prediction","subitem_subject_scheme":"Other"},{"subitem_subject":"Langevin dynamics","subitem_subject_scheme":"Other"},{"subitem_subject":"Fragment assembly","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"\u8a00\u8a9e","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"\u8cc7\u6e90\u30bf\u30a4\u30d7","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A coarse-grained Langevin molecular dynamics approach to de novo protein structure prediction","item_titles":{"attribute_name":"\u30bf\u30a4\u30c8\u30eb","attribute_value_mlt":[{"subitem_title":"A coarse-grained Langevin molecular dynamics approach to de novo protein structure prediction"}]},"item_type_id":"10","owner":"1","path":["320/321/322"],"pubdate":{"attribute_name":"\u516c\u958b\u65e5","attribute_value":"2014-10-30"},"publish_date":"2014-10-30","publish_status":"0","recid":"18530","relation_version_is_last":true,"title":["A coarse-grained Langevin molecular dynamics approach to de novo protein structure prediction"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2021-03-01T16:38:12.449983+00:00"}