@article{oai:nagoya.repo.nii.ac.jp:02001411, author = {Huang Chi Hsien and Umegaki, Hiroyuki and Makino, Taeko and Uemura, Kazuki and Hayashi, Takahiro and Kitada, Tomoharu and Inoue, Aiko and Shimada, Hiroyuki and Kuzuya, Masafumi}, issue = {6}, journal = {Age and Ageing}, month = {Nov}, note = {Background: Physical exercise has been linked to reduced frailty, but there is insufficient evidence of beneficial effects in community-dwelling older adults with subjective cognitive concerns. Objective: This study aimed to clarify the effects of physical exercise in this population. Design: Single-blind randomised controlled trial. Setting: Community sports centres. Participants: Residents aged 65–85 years were screened using the Kihon checklist; those with subjective cognitive concerns were invited for eligibility assessment. In total, 415 community-dwelling older adults were enrolled and randomised. Methods: This trial investigated the effects of aerobic training (AT), resistance training (RT) and combined training (AT+RT) programs on reducing frailty. All participants were randomised into one of the three intervention groups or the control group. Participants in the intervention groups underwent a group training program and self-paced home training for 26 weeks. The control group received lectures about health promotion. A 95-item frailty index (FI) was utilised to determine the effects of training. Participants were followed up at weeks 26 and 52. Results: At baseline, mean age of all participants (47% women) was 72.3 ± 4.6 years, with a mean FI score of 0.3 ± 0.1. Compared with control group, AT improved total FI by 0.020 (CI −0.039 to −0.001, effect size −0.275) and the depression and anxiety component of FI by 0.051 (CI −0.084 to −0.018, effect size −0.469) at week 26, but the effects waned at week 52. No significant differences in FI were found in RT and AT+RT groups at weeks 26 and 52. Conclusions: A 26-week AT reduced frailty modestly, especially in the depression and anxiety component, in older adults with subjective cognitive concerns.}, pages = {1011--1019}, title = {Effect of various exercises on frailty among older adults with subjective cognitive concerns: a randomised controlled trial}, volume = {49}, year = {2020} }