{"created":"2021-12-03T01:40:55.402477+00:00","id":2001662,"links":{},"metadata":{"_buckets":{"deposit":"442c720c-44e4-4d2d-ac39-2c20b291035f"},"_deposit":{"created_by":17,"id":"2001662","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"2001662"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:02001662","sets":["499:508:509:1638493189962"]},"author_link":[],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"825","bibliographicPageStart":"811","bibliographicVolumeNumber":"83","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"The Tokai Study Group for Therapeutic Radiology and Oncology (TOSTRO) started managing T1 glottic cancer using 2.25 Gy/fraction radiotherapy in 2011. The aim was to evaluate the local control (LC) rate and toxicity with 2.25-Gy radiotherapy in clinical practice and identify prognostic factors.The eligibility criteria were T1 glottic squamous cell carcinoma patients with age ≥20 years, treated with 2.25 Gy/fraction without chemotherapy between 2011 and 2017. LC rates were evaluated based on age, performance status, sex, T-category, tumor type (ulcerative or non-ulcerative), presence of anterior commissure invasion, tumor size, X-ray beam energy, and overall treatment time. Acute and late adverse events were evaluated using CTCAE version 4.0. A total of 202 patients were enrolled. The median follow-up period was 34.2 months. The 2- and 4-year LC rates were 93.8% and 93.1%, respectively. There was a significant difference in the LC rate between non-ulcerative type and ulcerative type (95.2% vs. 74.1% at 2 years, 94.4% vs. 74.1% at 4 years; p = 0.01). On univariate analysis, only tumor type was significantly correlated with a poor LC rate (hazard ratio 4.3; 95% confidence interval 1.2–15.4; p = 0.03). Acute grade 3 adverse events occurred in 17 patients. However, no late adverse events of grade 3 or higher have occurred to date. T1 glottic cancer treatment outcomes using hypofractionated radiotherapy with 2.25 Gy/fraction in clinical practice were comparable to previously reported results. However, ulcerative type tumor was associated with a poor LC rate.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.83.4.811","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University Graduate School of Medicine, School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/834.html","subitem_relation_type_select":"URI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International","subitem_rights_language":"en","subitem_rights_resource":"http://creativecommons.org/licenses/by-nc-nd/4.0/"}]},"item_9_source_id_7":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oie, Yumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Itoh, Yoshiyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kawamura, Mariko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Takase, Yuuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Murao, Takayuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ishihara, Shunichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nomoto, Yoshihito","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hirasawa, Naoki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Asano, Akiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yamakawa, Kouji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ito, Junji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kinoshita, Fumie","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Naganawa, Shinji","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-12-03"}],"displaytype":"detail","filename":"15_Oie.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/2001662/files/15_Oie.pdf"},"version_id":"60d3a179-f7ef-405e-8059-b9aebdc804a5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"T1 glottic cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hypofractionated radiotherapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"2.25 Gy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ulcerative tumor type","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Poor local control of ulcerative T1 glottic cancer treated with 2.25-Gy per fraction radiotherapy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Poor local control of ulcerative T1 glottic cancer treated with 2.25-Gy per fraction radiotherapy","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"17","path":["1638493189962"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-12-03"},"publish_date":"2021-12-03","publish_status":"0","recid":"2001662","relation_version_is_last":true,"title":["Poor local control of ulcerative T1 glottic cancer treated with 2.25-Gy per fraction radiotherapy"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T01:56:38.441077+00:00"}