{"created":"2021-12-06T06:22:14.225726+00:00","id":2001673,"links":{},"metadata":{"_buckets":{"deposit":"0fe8541c-615e-452a-aae6-feab8f992a68"},"_deposit":{"created_by":17,"id":"2001673","owner":"17","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"2001673"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:02001673","sets":["499:500:501"]},"author_link":[],"control_number":"2001673","item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1629683748249":{"attribute_name":"日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2022-06-01","subitem_date_issued_type":"Available"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"78","bibliographicPageStart":"73","bibliographicVolumeNumber":"24","bibliographic_titles":[{"bibliographic_title":"Pregnancy Hypertension","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Objectives: To determine the trajectories of platelet counts and the prevalence of gestational thrombocytopenia (<150 × 10^9/L) during normal pregnancies and pregnancies with complications, such as hypertensive disorders of pregnancy (HDP), preeclampsia, and fetal growth restriction (FGR). Study design: A multicenter retrospective study was conducted using laboratory data on women who delivered term singletons at 11 primary maternity care units between 2011 and 2018 (n = 35,045), and non-pregnant women who underwent a medical check-up between 2016 and 2019 (n = 61,189). After 1:1 matching, 28,073 pregnant women and 28,073 non-pregnant women were selected for analysis. Main outcomes measures: The trajectories of platelet counts and prevalence of gestational thrombocytopenia were evaluated in normal pregnant women, pregnant women with complications, and non-pregnant women. Results: The platelet counts declined throughout pregnancy, with the nadir occurring on postpartum day 1. The platelet counts recovered to the level of the non-pregnant state at postpartum 2–7 days. The mean platelet counts at postpartum day 1 decreased by an estimated 19.8% and 9.7% compared to those in the non-pregnant state and first trimester, respectively. The prevalence of gestational thrombocytopenia in normal pregnant women at 37–41 gestational weeks and in pregnant women with complications of HDP, preeclampsia, and FGR were 6.1%, 7.3%, 17.5%, and 7.7%, respectively. Conclusion: Platelet counts declined throughout pregnancy and recovered to the level of the non-pregnant state in the early postpartum period. Gestational thrombocytopenia is common during normal pregnancy, and its prevalence is significantly higher in women with preeclampsia.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.preghy.2021.02.013","subitem_relation_type_select":"DOI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/","subitem_rights_language":"en"}]},"item_9_source_id_7":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"2210-7789","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ushida, Takafumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kotani, Tomomi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Moriyama, Yoshinori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Imai, Kenji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakano-Kobayashi, Tomoko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kinoshita, Fumie","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakamura, Noriyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Iitani, Yukako","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yoshida, Shigeru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yamashita, Mamoru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kajiyama, Hiroaki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-06-01"}],"displaytype":"detail","filename":"Platelet_counts_during_pregnancy_revised_clean_version.pdf","filesize":[{"value":"458 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/2001673/files/Platelet_counts_during_pregnancy_revised_clean_version.pdf"},"version_id":"9dcc4f33-ed59-43f3-9b12-8170a6bc9cc1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Fetal growth restriction","subitem_subject_scheme":"Other"},{"subitem_subject":"Gestational thrombocytopenia","subitem_subject_scheme":"Other"},{"subitem_subject":"Hypertensive disorders of pregnancy","subitem_subject_scheme":"Other"},{"subitem_subject":"Platelet count","subitem_subject_scheme":"Other"},{"subitem_subject":"Preeclampsia","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Platelet counts during normal pregnancies and pregnancies complicated with hypertensive disorders","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Platelet counts during normal pregnancies and pregnancies complicated with hypertensive disorders","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"17","path":["501"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-12-06"},"publish_date":"2021-12-06","publish_status":"0","recid":"2001673","relation_version_is_last":true,"title":["Platelet counts during normal pregnancies and pregnancies complicated with hypertensive disorders"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-01-16T05:06:48.236940+00:00"}