{"created":"2022-05-27T00:56:11.277568+00:00","id":2002875,"links":{},"metadata":{"_buckets":{"deposit":"134d26aa-2603-4d2a-a0b6-42a3b33dec5f"},"_deposit":{"created_by":17,"id":"2002875","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"2002875"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:02002875","sets":["499:508:509:1653611787117"]},"author_link":[],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"246","bibliographicPageStart":"230","bibliographicVolumeNumber":"84","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"This study determined prognostic factors by comparing clinico-bacterial factors based on significant elevated serum procalcitonin levels in patients with suspected bloodstream infection (BSI). We retrospectively analyzed the medical records of 1,052 patients (age ≥16 years) with fever (temperature ≥38°C) and serum procalcitonin levels of ≥2.0 ng/mL, and blood culture results. The optimal cutoff value of the significant elevation of procalcitonin was determined using the minimum P-value approach. Clinico-bacterial factors were analyzed per the procalcitonin levels, and significant independent factors for short-term survival were investigated in 445 patients with BSI. Patients with suspected BSI were aged, on average, 72.3 ±15.1 years, and the incidence of positive blood culture was 42.3%; and the 14-day survival was 83.4%. Procalcitonin ≥100 ng/mL was the most significant predictor for survival. Multivariate analysis in patients with suspected BSI showed that estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m^2 and procalcitonin ≥100 ng/mL were significant independent unfavorable prognostic factors. Microorganisms were similar between patients with procalcitonin level 2–99 ng/mL (n=359) and those with ≥100 ng/mL (n=86). Multivariate analysis in patients with BSI showed that eGFR <30 mL/min/1.73 m^2, procalcitonin ≥100 ng/mL, and primary infectious foci were significant independent prognostic factors. Patients with foci in the gastrointestinal tract and respiratory system had unfavorable 14-day survival. In conclusions, eGFR <30 mL/min/1.73 m^2 and procalcitonin ≥100 ng/mL were significant independent unfavorable prognostic factors for suspected BSI. Primary infectious foci (gastrointestinal tract and respiratory system) were associated with unfavorable short-term survival in patients with positive blood culture.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.84.2.230","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University Graduate School of Medicine, School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/842.html","subitem_relation_type_select":"URI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International","subitem_rights_language":"en","subitem_rights_resource":"http://creativecommons.org/licenses/by-nc-nd/4.0/"}]},"item_9_source_id_7":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Osamura, Yoko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nishiyama, Hideki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hattori, Takuya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Gunji, Masaharu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yuasa, Norihiro","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-05-27"}],"displaytype":"detail","filename":"03_Osamura.pdf","filesize":[{"value":"2.8 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/2002875/files/03_Osamura.pdf"},"version_id":"effa7d14-8d13-46a8-80da-4b487a89cfa3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"procalcitonin","subitem_subject_scheme":"Other"},{"subitem_subject":"bloodstream infection","subitem_subject_scheme":"Other"},{"subitem_subject":"survival","subitem_subject_scheme":"Other"},{"subitem_subject":"renal function","subitem_subject_scheme":"Other"},{"subitem_subject":"blood culture","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Clinico-bacterial and prognostic factors in patients with suspected blood stream infection and elevated serum procalcitonin levels","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clinico-bacterial and prognostic factors in patients with suspected blood stream infection and elevated serum procalcitonin levels","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"17","path":["1653611787117"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-05-27"},"publish_date":"2022-05-27","publish_status":"0","recid":"2002875","relation_version_is_last":true,"title":["Clinico-bacterial and prognostic factors in patients with suspected blood stream infection and elevated serum procalcitonin levels"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T01:57:52.717511+00:00"}