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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Hybrid 3D T1-weighted gradient-echo sequence for fiducial marker detection and tumor delineation via magnetic resonance imaging in liver stereotactic body radiation therapy

http://hdl.handle.net/2237/0002003008
http://hdl.handle.net/2237/0002003008
982dbec6-03c3-4256-99d0-87afdf43fc51
名前 / ファイル ライセンス アクション
Repository_Kato_Y_et_al_Phys_Med_2022.pdf Repository_Kato_Y_et_al_Phys_Med_2022.pdf (1.3 MB)
 Download is available from 2023/2/28.
Item type itemtype_ver1(1)
公開日 2022-06-23
タイトル
タイトル Hybrid 3D T1-weighted gradient-echo sequence for fiducial marker detection and tumor delineation via magnetic resonance imaging in liver stereotactic body radiation therapy
言語 en
著者 Kato, Yutaka

× Kato, Yutaka

en Kato, Yutaka

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Kamomae, Takeshi

× Kamomae, Takeshi

en Kamomae, Takeshi

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Kumagai, Motoki

× Kumagai, Motoki

en Kumagai, Motoki

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Oie, Yumi

× Oie, Yumi

en Oie, Yumi

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Noguchi, Yumiko

× Noguchi, Yumiko

en Noguchi, Yumiko

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Okudaira, Kuniyasu

× Okudaira, Kuniyasu

en Okudaira, Kuniyasu

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Kawamura, Mariko

× Kawamura, Mariko

en Kawamura, Mariko

Search repository
Taoka, Toshiaki

× Taoka, Toshiaki

en Taoka, Toshiaki

Search repository
Naganawa, Shinji

× Naganawa, Shinji

en Naganawa, Shinji

Search repository
アクセス権
アクセス権 embargoed access
アクセス権URI http://purl.org/coar/access_right/c_f1cf
権利
言語 en
権利情報 © 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
キーワード
主題Scheme Other
主題 Liver stereotactic body radiation therapy
キーワード
主題Scheme Other
主題 Gold fiducial marker
キーワード
主題Scheme Other
主題 Marker detection
キーワード
主題Scheme Other
主題 EOB-MRI
内容記述
内容記述 Purpose: Gold fiducial markers are used to guide liver stereotactic body radiation therapy (SBRT) and are hard to detect by magnetic resonance imaging (MRI). In this study, the parameters of the three-dimensional T1-weighted turbo gradient-echo (3D T1W-GRE) sequence were optimized for gold marker detection without degrading tumor delineation. Methods: Custom-made phantoms mimicking tumor and normal liver parenchyma were prepared and embedded with a gold marker. The 3D T1W-GRE was scanned by varying echo time (TE), bandwidth (BW), flip angle (FA), and base matrix size. The signal-to-noise ratio (SNR), contrast ratio (CR), and relative standard deviation (RSD) of the signal intensity in the area including the gold marker were evaluated, and the parameters were optimized accordingly. The modified 3D T1W-GRE (called HYBRID) was compared with the conventional T1W-GRE- and T2*-sequences in both phantom and clinical studies. In the clinical study of six patients with primary liver tumors, two observers visually assessed marker detection, tumor delineation, and overall image quality on a four-point scale. Results: In the phantom study, HYBRID showed significantly higher SNR and RSD than those of conventional T1W-GRE (P < 0.001). In the clinical study, HYBRID yielded significantly higher scores than conventional T1W-GRE did in terms of marker detection (P < 0.001). The scores of both sequences were not statistically different in terms of tumor delineation and overall image quality (P = 0.56 and P = 0.32). Conclusions: The proposed HYBRID sequence improved gold fiducial marker detection without degrading tumor delineation in MRI for SBRT of primary liver tumor.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.ejmp.2022.01.003
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 1120-1797
書誌情報 en : Physica Medica

巻 95, p. 9-15, 発行日 2022-03
ファイル公開日
日付 2023-03-01
日付タイプ Available
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