Item type |
itemtype_ver1(1) |
公開日 |
2022-07-19 |
タイトル |
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タイトル |
Influence of frailty on patient global assessment in rheumatoid arthritis |
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言語 |
en |
著者 |
Suzuki, Mochihito
Asai, Shuji
Sobue, Yasumori
Ohashi, Yoshifumi
Koshima, Hiroshi
Okui, Nobuyuki
Ishikawa, Hisato
Takahashi, Nobunori
Terabe, Kenya
Kishimoto, Kenji
Hattori, Kyosuke
Imagama, Shiro
Kojima, Toshihisa
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利 |
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言語 |
en |
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権利情報 |
"This is the peer reviewed version of the following article: [Suzuki, M, Asai, S, Sobue, Y, et al. Influence of frailty on patient global assessment in rheumatoid arthritis. Geriatr. Gerontol. Int. 2022; 22: 399–404. https://doi.org/10.1111/ggi.14375], which has been published in final form at [https://doi.org/10.1111/ggi.14375]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited." |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Aim: Patient Global Assessment (PtGA; range 0–10 cm) is an important indicator of clinical outcomes, including physical function, in self-assessment of patients with rheumatoid arthritis (RA). Frailty is a concept that encompasses not only physical, but also mental, psychological and social vulnerability. This study aimed to investigate the influence of frailty on PtGA in patients with RA. Methods: Among 581 patients with RA who completed a questionnaire survey on frailty between June and August 2020, 559 who completed the Kihon Checklist (KCL; a 25-item questionnaire with seven domains) were included. The proportion of patients with PtGA ≤1 was compared between the frailty (KCL score ≥8), pre-frailty (KCL score 4–7) and robust (KCL score 0–3) groups. Factors associated with PtGA ≤1 were examined using multivariate logistic regression models. Results: Of the 559 patients, 221 (39.5%) had frailty. The proportion of patients with PtGA ≤1 was significantly lower in the frailty group (33.9%) than in the robust (65.4%, P < 0.001) and pre-frailty (55.7%, P < 0.001) groups. Multivariate analysis revealed that frailty (vs robust, OR 0.37, 95% CI 0.22–0.69), as well as disease duration and tender joint count, were factors independently associated with PtGA ≤1. When each domain of the KCL was examined, activities of daily living, physical strength, isolation and depressive mood were factors associated with PtGA ≤1. Conclusion: Frailty affects PtGA in patients with RA. As frailty impacts the physical, mental and social vulnerability aspects of PtGA, a multifaceted approach, including inflammation suppression, is required to improve PtGA in patients with RA. Geriatr Gerontol Int 2022; 22: 399–404. |
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言語 |
en |
出版者 |
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出版者 |
Wiley |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1111/ggi.14375 |
収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1444-1586 |
書誌情報 |
en : Geriatrics & Gerontology International
巻 22,
号 5,
p. 399-404,
発行日 2022-05
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ファイル公開日 |
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日付 |
2023-05-01 |
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日付タイプ |
Available |