@article{oai:nagoya.repo.nii.ac.jp:02003742, author = {Sone, Michihiko and Yoshida, Tadao and Sugimoto, Satofumi and Kobayashi, Masumi and Teranishi, Masaaki and Naganawa, Shinji}, issue = {3}, journal = {Nagoya Journal of Medical Science}, month = {Aug}, note = {We summarize the presence of endolymphatic hydrops (EH) in otological disorders evaluated with magnetic resonance imaging (MRI) of temporal bones, and propose a classification of EH based on its pathological significance. A search of the literature published in English-language journals was performed using electronic databases, especially focusing on EH-related otological disorders. Clinical articles that contained the terms EH and contrast-MRI published from 2007 to the present, with relevant human temporal bone studies, were included. The following three main points are discussed based on the results in the relevant articles: i) otological disorders that present EH, ii) current grading for evaluation of EH on MRI, and iii) a proposed classification of EH based on its pathological significance. MRI evaluation revealed that EH exists extensively not only in ears with typical Meniere’s disease (MD), but also in those with various other otological disorders. The etiological classification of EH helps to summarize ideas for determining the pathophysiology of otological disorders, while a therapeutic classification provides clues to their management. MRI evaluations of EH have led to breakthroughs in investigations of EH in otological disorders. Precise grading for evaluation and clarification of EH on MRI based on its pathological significance could provide keys to elucidating the pathophysiology of EH-related otological disorders.}, pages = {497--505}, title = {Pathological significance and classification of endolymphatic hydrops in otological disorders}, volume = {84}, year = {2022} }