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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Physiological background parenchymal uptake of 18F-FDG in normal breast tissues using dedicated breast PET: correlation with mammographic breast composition, menopausal status, and menstrual cycle

http://hdl.handle.net/2237/0002003917
http://hdl.handle.net/2237/0002003917
cb6651ad-d0c9-47a6-a1be-7717f102dac8
名前 / ファイル ライセンス アクション
ANNALS_OF_NUCLEAR_MEDICINE_shimizu.pdf ANNALS_OF_NUCLEAR_MEDICINE_shimizu.pdf (413 KB)
 Download is available from 2023/7/31.
Item type itemtype_ver1(1)
公開日 2022-10-13
タイトル
タイトル Physiological background parenchymal uptake of 18F-FDG in normal breast tissues using dedicated breast PET: correlation with mammographic breast composition, menopausal status, and menstrual cycle
言語 en
著者 Shimizu, Yuri

× Shimizu, Yuri

en Shimizu, Yuri

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Satake, Hiroko

× Satake, Hiroko

en Satake, Hiroko

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Ishigaki, Satoko

× Ishigaki, Satoko

en Ishigaki, Satoko

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Shimamoto, Kazuhiro

× Shimamoto, Kazuhiro

en Shimamoto, Kazuhiro

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Uota, Fuga

× Uota, Fuga

en Uota, Fuga

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Tadokoro, Masanori

× Tadokoro, Masanori

en Tadokoro, Masanori

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Sato, Tomohiro

× Sato, Tomohiro

en Sato, Tomohiro

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Kato, Katsuhiko

× Kato, Katsuhiko

en Kato, Katsuhiko

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Ishiguchi, Tsuneo

× Ishiguchi, Tsuneo

en Ishiguchi, Tsuneo

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Naganawa, Shinji

× Naganawa, Shinji

en Naganawa, Shinji

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アクセス権
アクセス権 embargoed access
アクセス権URI http://purl.org/coar/access_right/c_f1cf
権利
言語 en
権利情報 This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s12149-022-01754-4
内容記述
内容記述 Objective: This study aimed to quantitatively evaluate the effects of age, mammographic density, menopausal status, and menstrual cycle on background parenchymal uptake (BPU) using ring-shaped dedicated breast positron emission tomography (dbPET). Methods: This study included 186 adult women who underwent mammography and dbPET on the same day and had no abnormalities classified as Breast Imaging Reporting and Data System (BI-RADS) category 1 on both examinations. The volume of interest (VOI) was placed in the glandular tissue of both breasts, and the maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), and metabolic breast volume (MBV) were measured as indicators of BPU. We analyzed the correlation between BPU and age, mammographic density, menopausal status, and menstrual cycle. Results: The SUVmax and SUVmean for normal breast tissue were inversely correlated with age (both p < 0.001). The SUVmax, SUVmean, and MBV of mammographically dense breast tissues were significantly higher than those of non-dense breast tissues (all p < 0.001). The SUVmax, SUVmean, and MBV of normal breast tissue in premenopausal women were significantly higher than those in postmenopausal women (p < 0.001, p < 0.001, p = 0.002, respectively). In the study, 59 premenopausal women, the SUVmax of normal breast tissue in the menstrual-follicular phase was significantly lower than that in the periovulatory-luteal phase (p = 0.02). When we sorted the premenopausal women by mammographic breast composition, the SUVmax and SUVmean of normal breast tissues in the menstrual-follicular phase were significantly lower than those in the periovulatory-luteal phase in the 44 premenopausal women with dense breasts (p = 0.007, and p = 0.038, respectively), whereas no statistically significant difference was found between the menstrual-follicular phase and the periovulatory-luteal phase in the 15 premenopausal women with non-dense breasts. Conclusions: BPU in normal breast tissues assessed using ring-shaped dbPET was associated with mammographic density, menopausal status, and women’s menstrual cycle. The menstrual cycle was significantly associated with BPU in premenopausal women with dense breasts but not in women with non-dense breasts.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Springer
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1007/s12149-022-01754-4
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0914-7187
書誌情報 en : Annals of Nuclear Medicine

巻 36, 号 8, p. 728-735, 発行日 2022-08
ファイル公開日
日付 2023-08-01
日付タイプ Available
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