{"created":"2022-11-22T05:59:16.593219+00:00","id":2004213,"links":{},"metadata":{"_buckets":{"deposit":"64e64188-5496-4d5b-8c45-3b7a2084daf7"},"_deposit":{"id":"2004213","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2004213"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:02004213","sets":["499:508:509:1669094631719"]},"author_link":[],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"870","bibliographicPageStart":"865","bibliographicVolumeNumber":"84","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Undifferentiated carcinoma of the bladder is a rare malignancy with a poor prognosis. We present the case of an 81-year-old woman complaining of bladder irritation. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a bulky bladder tumor, which was diagnosed as cT4aN0M0. A transurethral resection of the bladder tumor revealed pT2 or higher urothelial carcinoma. The patient underwent total cystectomy with an ileal conduit diversion. Histological examination revealed a primary undifferentiated bladder carcinoma with a sarcoma component, pT3aN0M0. Postoperative adjuvant chemotherapy with gemcitabine plus carboplatin was administered. However, this regimen was discontinued after one course due to significant myelosuppression. Four months after total cystectomy, a pelvic tumor with suspected local recurrence was detected on CT. The patient was diagnosed with recurrent undifferentiated carcinoma with a sarcoma component by a transperineal ultrasound-guided biopsy. Local radiation therapy and immunotherapy with immune checkpoint inhibitors were prescribed. After three courses of immunotherapy with pembrolizumab, the primary tumor disappeared. Upon continuing immune checkpoint inhibitor treatment, the patient has maintained a complete response without tumor recurrence in the following six months.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.84.4.865","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University Graduate School of Medicine, School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/844.html","subitem_relation_type_select":"URI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International","subitem_rights_language":"en","subitem_rights_resource":"http://creativecommons.org/licenses/by-nc-nd/4.0/"}]},"item_9_source_id_7":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakane, Wataru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Naito, Yushi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Morishita, Koya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Matsuo, Kazuna","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ishida, Shohei","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Matsukawa, Yoshihisa","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-11-24"}],"displaytype":"detail","filename":"17_Nakane.pdf","filesize":[{"value":"23.2 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/2004213/files/17_Nakane.pdf"},"version_id":"507e35fc-f150-4576-bd75-4e31e7586212"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"undifferentiated carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"bladder","subitem_subject_scheme":"Other"},{"subitem_subject":"immune checkpoint inhibitors","subitem_subject_scheme":"Other"},{"subitem_subject":"radiation therapy","subitem_subject_scheme":"Other"},{"subitem_subject":"abscopal effect","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A case of undifferentiated carcinoma of the bladder treated by combination therapy of surgery, local radiation, and immune checkpoint inhibitors","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A case of undifferentiated carcinoma of the bladder treated by combination therapy of surgery, local radiation, and immune checkpoint inhibitors","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"1","path":["1669094631719"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-11-22"},"publish_date":"2022-11-22","publish_status":"0","recid":"2004213","relation_version_is_last":true,"title":["A case of undifferentiated carcinoma of the bladder treated by combination therapy of surgery, local radiation, and immune checkpoint inhibitors"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-04-28T06:33:52.580325+00:00"}