{"created":"2022-11-30T01:19:09.649288+00:00","id":2004232,"links":{},"metadata":{"_buckets":{"deposit":"be29607c-6fb3-473d-9c5e-99bbd8472557"},"_deposit":{"created_by":17,"id":"2004232","owner":"17","owners":[17],"owners_ext":{"displayname":"repository","username":"repository"},"pid":{"revision_id":0,"type":"depid","value":"2004232"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:02004232","sets":["499:500:501"]},"author_link":[],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1629683748249":{"attribute_name":"日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2024-11-01","subitem_date_issued_type":"Available"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-11","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"135571","bibliographicVolumeNumber":"306","bibliographic_titles":[{"bibliographic_title":"Chemosphere","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Hexavalent chromium [Cr(VI)], which has a strong corrosive effect, has been reported to cause perforation of the eardrum. Trivalent chromium [Cr(III)] also has a weak corrosive effect. However, there has been no study on the effects of exposure to Cr, either Cr(VI) or Cr(III), on hearing levels in animals or humans. In this study, the effect of Cr(III) exposure on hearing levels was determined in a human study. Then the reproducibility of the results obtained in the human study and the etiology were investigated in an animal study. The mean levels of total chromium (t-Cr) in hair and toenails from 100 Bangladeshi tannery workers were >20-fold and >360-fold higher, respectively, than those in hair and toenails from 49 Bangladeshi non-tannery workers (office workers). Multivariate analysis revealed decreases of hearing levels (DHLs) at 1 k and 4 k Hz, frequencies that are crucial for understanding language, but not at 8 k and 12 k Hz, in the tannery workers. Since >99.99% of t-Cr in the wastewater that the workers were in direct contact with in the tanneries was Cr(III), the epidemiological results suggest Cr(III)-mediated DHLs in the tannery workers. The results of animal experiments in this study further showed that treatment with eardrops but not intraperitoneal injection with the same amount of Cr(III) that tannery workers might be exposed to resulted in DHL with a damaged eardrum in mice. Previous studies suggested that Cr(III) can directly reach the eardrums of tannery workers via droplets in the air. Cr(III) could also reach the eardrum via picking an ear canal with a finger contaminated with tannery wastewater including Cr(III). Taken together, the results of both human and animal studies suggest the risk of DHLs caused by damage of the eardrum through external exposure to Cr(III) via the ear canal.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.chemosphere.2022.135571","subitem_relation_type_select":"DOI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/","subitem_rights_language":"en"}]},"item_9_source_id_7":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"0045-6535","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"embargoed access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_f1cf"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Gu, Yishuo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ohgami, Nobutaka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Al Hossain, M.M. Aeorangajeb","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tazaki, Akira","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tsuchiyama, Tomoyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"He, Tingchao","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Aoki, Masayo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ahsan, Nazmul","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Akhand, Anwarul Azim","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kato, Masashi","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2024-11-01"}],"displaytype":"detail","filename":"Gu_et_al_Chemosphere_2022_Manuscript_Final_version.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","url":{"objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/2004232/files/Gu_et_al_Chemosphere_2022_Manuscript_Final_version.pdf"},"version_id":"ca7f70d9-a289-4a66-aa6a-b533647ef224"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2024-11-01"}],"displaytype":"detail","filename":"Supplementary_figures_Gu_et_al_Chemosphere_2022.pdf","filesize":[{"value":"649 KB"}],"format":"application/pdf","url":{"objectType":"dataset","url":"https://nagoya.repo.nii.ac.jp/record/2004232/files/Supplementary_figures_Gu_et_al_Chemosphere_2022.pdf"},"version_id":"2abd4bdd-a790-4232-9598-26ed65f16ba2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Decreased hearing levels at frequencies for understanding speech in tannery workers exposed to a high level of trivalent chromium in Bangladesh","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Decreased hearing levels at frequencies for understanding speech in tannery workers exposed to a high level of trivalent chromium in Bangladesh","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"17","path":["501"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-11-30"},"publish_date":"2022-11-30","publish_status":"0","recid":"2004232","relation_version_is_last":true,"title":["Decreased hearing levels at frequencies for understanding speech in tannery workers exposed to a high level of trivalent chromium in Bangladesh"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-01-16T05:03:07.108281+00:00"}