@article{oai:nagoya.repo.nii.ac.jp:02004240,
 author = {Itoh, Hayato and Misawa, Masashi and Mori, Yuichi and Kudo, Shin-Ei and Oda, Masahiro and Mori, Kensaku},
 issue = {11},
 journal = {International Journal of Computer Assisted Radiology and Surgery},
 month = {Nov},
 note = {Purpose: Precise polyp detection and localisation are essential for colonoscopy diagnosis. Statistical machine learning with a large-scale data set can contribute to the construction of a computer-aided diagnosis system for the prevention of overlooking and miss-localisation of a polyp in colonoscopy. We propose new visual explaining methods for a well-trained object detector, which achieves fast and accurate polyp detection with a bounding box towards a precise automated polyp localisation. Method: We refine gradient-weighted class activation mapping for more accurate highlighting of important patterns in processing a convolutional neural network. Extending the refined mapping into multiscaled processing, we define object activation mapping that highlights important object patterns in an image for a detection task. Finally, we define polyp activation mapping to achieve precise polyp localisation by integrating adaptive local thresholding into object activation mapping. We experimentally evaluate the proposed visual explaining methods with four publicly available databases. Results: The refined mapping visualises important patterns in each convolutional layer more accurately than the original gradient-weighted class activation mapping. The object activation mapping clearly visualises important patterns in colonoscopic images for polyp detection. The polyp activation mapping localises the detected polyps in ETIS-Larib, CVC-Clinic and Kvasir-SEG database with mean Dice scores of 0.76, 0.72 and 0.72, respectively. Conclusions: We developed new visual explaining methods for a convolutional neural network by refining and extending gradient-weighted class activation mapping. Experimental results demonstrated the validity of the proposed methods by showing that accurate visualisation of important patterns and localisation of polyps in a colonoscopic image. The proposed visual explaining methods are useful for the interpreting and applying a trained polyp detector.},
 pages = {2051--2063},
 title = {Positive-gradient-weighted object activation mapping: visual explanation of object detector towards precise colorectal-polyp localisation},
 volume = {17},
 year = {2022}
}