@article{oai:nagoya.repo.nii.ac.jp:02005106,
 author = {久保田, 正和 and KUBOTA, Masakazu and 越中, 敬一 and KOSHINAKA, Keiichi and 秦, 柏林 and QIN, Bolin and 大澤, 功 and OSAWA, Isao and 小池, 晃彦 and KOIKE, Akihiko and 押田, 芳治 and OSHIDA, Yoshiharu},
 issue = {1},
 journal = {総合保健体育科学, Nagoya Journal of Health, Physical Fitness & Sports},
 month = {Mar},
 note = {Aging is associated with insulin resistance, but the exact molecular mechanism is unknown. The serine/threonine kinase Akt, which is functionally located downstream of the PI3-kinase has been implicated as playing a role in the insulin-signaling pathway to glucose transport. In the present study, we examined the Akt protein levels and the effect of insulin on Akt kinase activity in rat extensor digitorum longus and soleus muscles between 12-week and 30-month-old rats. There were no significant differences in the Akt protein levels and the Akt activity after insulin stimulation between 12-week- and 30-month-old rats in both skeletal muscles. These data suggest that the Akt protein levels and the Akt activity after insulin stimulation in aged rat were maintained in skeletal muscle.},
 pages = {9--13},
 title = {加齢が骨格筋のインスリン作用に及ぼす影響},
 volume = {28},
 year = {2005}
}