@article{oai:nagoya.repo.nii.ac.jp:02005230,
 author = {北越, 香織 and KITAKOSHI, kaori and 押田, 芳治 and OSHIDA, Yoshiharu and 韓, 艶清 and HAN, Yanqing and 福, 典之 and FUKU, Noriyuki and 佐藤, 祐造 and SATO, Yuzo},
 issue = {1},
 journal = {総合保健体育科学, Nagoya Journal of Health, Physical Fitness & Sports},
 month = {Mar},
 note = {This study was undertaken in order to investigate the influences of high-fat and high-fructose diets on insulin resistance. Female Wistar rats were fed high-fat, high-fructose diet or control chow diet ad libitum for 3wks. Insulin action was assessed with the euglycemic clamp (insulin infusion rate: 3.0 (L) and 30.0 (H) mU/kg BW/min). Blood glucose levels in all groups were kept constant during the euglycemic clamp. In the L-clamp, glucose infusion rate (GIR) in high-fat fed rats was decreased significantly, as compared with controls (4.7±0.1 vs. 8.3±0.1 mg/kg BW/min, P<0.001). High-fructose feeding (3.4±0.1 mg/kg BW/min) also attenuated GIR compared with controls (P<0.001). In the H-clamp, GIR in high-fat fed rats was similar to that in high-fructose fed rats, but GIRs in these animals were significantly decreased (6.5±0.4, 6.4±0.5 vs. 11.5±0.4 mg/kg BW/min, P<0.001). These results indicate that insulin resistance is induced by both high-fat and high-fructose feedings.},
 pages = {19--21},
 title = {食餌組成の相違がインスリン作用に及ぼす影響},
 volume = {23},
 year = {2000}
}