@article{oai:nagoya.repo.nii.ac.jp:02005514, author = {呉, 瑋 and WU, Wei and 押田, 芳治 and OSHIDA, Yoshiharu and 楊, 衛平 and YANG, Wei-Ping and 佐藤, 寿一 and SATO, Juichi and 大沢, 功 and OHSAWA, Isao and 佐藤, 祐造 and SATO, Yuzo}, issue = {1}, journal = {総合保健体育科学, Nagoya Journal of Health, Physical Fitness & Sports}, month = {Mar}, note = {Physical training has been shown to improve insulin action in simple obese and diabetic patients. On the other hand, the hyperketonemic effect of prolonged exercise in insulin-dependent diabetic patients is a well recognized phenomenon. Therefore, in order to evaluate the mechanism, especially the effect of exercise in ketone body metabolism m muscle, we measured extracellular acetoacetate (AcAc) concentrations in muscle of five diabetic and five control rats. The following results were obtained; 1. In control rats, constriction produced a significant rise in dialysate AcAc concentration which rapidly returned to pre-constriction levels after constriction. 2. In diabetics, the dialysate AcAc concentrations showed a significant increase during constriction and for 60 min after constriction. These results suggest that exercise results in a significant reduction in ketone body utilization in muscle not only in diabetic but also control rats and a reduction in ketone body utilization after muscle constriction in poorly-controlled diabetics plays a role in post-exercise hyperketonemia.}, pages = {13--17}, title = {骨格筋におけるケトン体代謝に関する研究(第2報) : 運動筋におけるアセト酢酸の代謝変動}, volume = {16}, year = {1993} }