{"_buckets": {"deposit": "e0f57448-ec83-4cae-8754-71304191c267"}, "_deposit": {"created_by": 17, "id": "2007326", "owner": "17", "owners": [17], "owners_ext": {"displayname": "repository", "username": "repository"}, "pid": {"revision_id": 0, "type": "depid", "value": "2007326"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:02007326"}, "author_link": [], "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_1629683748249": {"attribute_name": "日付", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2024-07-01", "subitem_date_issued_type": "Available"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2023-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "1879", "bibliographicPageStart": "1875", "bibliographicVolumeNumber": "49", "bibliographic_titles": [{"bibliographic_title": "Journal of Obstetrics and Gynaecology Research", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "This study analyzed a 63-year-old woman with hereditary BRCA1 mutation. She underwent interval debulking surgery after neoadjuvant chemotherapy for high-grade serous ovarian carcinoma (HGSOC). After 2 years of postoperative chemotherapy, she developed headache and dizziness, and a suspected metastatic cerebellar mass in left ovary was detected. Pathological analysis of the mass revealed HGSOC, which was removed surgically. Eight months and another 6 months after the surgery, local recurrence was noted; hence, she underwent CyberKnife treatment. After 3 months, cervical spinal cord metastasis was found, evidenced by left shoulder pain. Moreover, meningeal dissemination was present around the cauda equina. Chemotherapy treatment, including bevacizumab, was ineffective and increased lesions were observed. After CyberKnife treatment for the cervical spinal cord metastasis, niraparib was initiated for the meningeal dissemination. The cerebellar lesions and meningeal dissemination improved within 8 months of niraparib treatment. Although meningeal dissemination is challenging to treat, niraparib may be useful in BRCA-mutated HGSOC.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier", "subitem_publisher_language": "en"}]}, "item_9_relation_43": {"attribute_name": "関連情報", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1111/jog.15663", "subitem_relation_type_select": "DOI"}}]}, "item_9_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "\"This is the peer reviewed version of the following article: [Nei, T, Tamauchi, S, Ikeda, Y, Yoshikawa, N, Niimi, K, Kajiyama, H. Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with BRCA1 mutation. J Obstet Gynaecol Res. 2023; 49(7): 1875–1879. https://doi.org/10.1111/jog.15663], which has been published in final form at [https://doi.org/10.1111/jog.15663]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\"", "subitem_rights_language": "en"}]}, "item_9_source_id_7": {"attribute_name": "収録物識別子", "attribute_value_mlt": [{"subitem_source_identifier": "1341-8076", "subitem_source_identifier_type": "PISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "embargoed access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_f1cf"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nei, Takashi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Tamauchi, Satoshi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Ikeda, Yoshiki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yoshikawa, Nobuhisa", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Niimi, Kaoru", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kajiyama, Hiroaki", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2024-07-01"}], "displaytype": "detail", "download_preview_message": "Download / Preview is available from 2024/6/30.", "file_order": 0, "filename": "revised_manuscript.pdf", "filesize": [{"value": "2 MB"}], "format": "application/pdf", "future_date_message": "Download is available from 2024/6/30.", "is_thumbnail": false, "mimetype": "application/pdf", "size": 2000000.0, "url": {"objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/2007326/files/revised_manuscript.pdf"}, "version_id": "69049c77-3eb3-451b-b7e6-8df9c0dd65cf"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with BRCA1 mutation", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with BRCA1 mutation", "subitem_title_language": "en"}]}, "item_type_id": "40001", "owner": "17", "path": ["501"], "permalink_uri": "http://hdl.handle.net/2237/0002007326", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2023-09-14"}, "publish_date": "2023-09-14", "publish_status": "0", "recid": "2007326", "relation": {}, "relation_version_is_last": true, "title": ["Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with BRCA1 mutation"], "weko_shared_id": -1}
Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with BRCA1 mutation
http://hdl.handle.net/2237/0002007326
http://hdl.handle.net/2237/0002007326