{"created":"2023-12-01T07:08:02.389827+00:00","id":2008451,"links":{},"metadata":{"_buckets":{"deposit":"4fce021f-104a-4de7-aed8-a80930572aea"},"_deposit":{"created_by":17,"id":"2008451","owner":"17","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"2008451"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:02008451","sets":["499:508:509:1701410469907"]},"author_link":[],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"835","bibliographicPageStart":"828","bibliographicVolumeNumber":"85","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Gliosarcoma (GS), a morphological variant of glioblastoma, pathologically shows a biphasic pattern with gliomatous and sarcomatous components. It has been reported that GS has much higher metastatic capacity than glioblastoma. A few reports on the pathology of the extracranial metastasis of GS have shown that metastatic lesions had a sarcomatous component alone or a mixture of gliomatous and sarcomatous ones. Therefore, it is considered that GS tends to disseminate hematogenously due to its mesenchymal sarcomatous component. Herein, we report an autopsy case of GS with multiple extracranial metastases treated by craniotomy, radiotherapy, and bevacizumab. In this case, metastatic lesions at autopsy contained a gliomatous component alone, but no sarcomatous component. In addition, the sarcomatous component disappeared from the intracranial lesion at autopsy after the administration of bevacizumab. In this report, we discuss the clinical course and pathological findings at the initial state, recurrence, and autopsy, including the results of whole-genome analysis.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.85.4.828","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University Graduate School of Medicine, School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/854.html","subitem_relation_type_select":"URI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International","subitem_rights_language":"en","subitem_rights_resource":"http://creativecommons.org/licenses/by-nc-nd/4.0/"}]},"item_9_source_id_7":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sato, Yoshiki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Deguchi, Shoichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Norose, Tomoko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Oishi, Takuma","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Mitsuya, Koichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sugino, Takashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Akiyama, Yasuto","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nagashima, Takeshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Urakami, Kenichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shimoda, Yuji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ohshima, Keiichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hayashi, Nakamasa","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yamaguchi, Ken","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-12-04"}],"displaytype":"detail","filename":"17_Sato.pdf","filesize":[{"value":"21.1 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/2008451/files/17_Sato.pdf"},"version_id":"9b1b9ff8-7af7-4aa7-baf3-e401e4476f31"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gliosarcoma","subitem_subject_scheme":"Other"},{"subitem_subject":"metastasis","subitem_subject_scheme":"Other"},{"subitem_subject":"bevacizumab","subitem_subject_scheme":"Other"},{"subitem_subject":"pathology","subitem_subject_scheme":"Other"},{"subitem_subject":"whole-genome analysis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An autopsy case of primary gliosarcoma with multiple extracranial metastases: pathology after administration of bevacizumab and genetic profile","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An autopsy case of primary gliosarcoma with multiple extracranial metastases: pathology after administration of bevacizumab and genetic profile","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"17","path":["1701410469907"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-12-04"},"publish_date":"2023-12-04","publish_status":"0","recid":"2008451","relation_version_is_last":true,"title":["An autopsy case of primary gliosarcoma with multiple extracranial metastases: pathology after administration of bevacizumab and genetic profile"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-12-04T05:13:31.876467+00:00"}