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  1. C100 医学部/医学系研究科
  2. C100b 刊行物
  3. Nagoya journal of medical science
  4. 86(2)

Pregnancy co-treated with oral gonadotropin-releasing hormone antagonist in a woman with premature ovarian insufficiency: a case report

https://doi.org/10.18999/nagjms.86.2.333
https://doi.org/10.18999/nagjms.86.2.333
97ee7dc1-5a89-4341-b1c5-c3722eacb575
名前 / ファイル ライセンス アクション
16_Inoue.pdf 16_Inoue.pdf (18.9 MB)
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アイテムタイプ itemtype_ver1(1)
公開日 2024-05-27
タイトル
タイトル Pregnancy co-treated with oral gonadotropin-releasing hormone antagonist in a woman with premature ovarian insufficiency: a case report
言語 en
著者 Inoue, Daichi

× Inoue, Daichi

en Inoue, Daichi

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Kondo, Manami

× Kondo, Manami

en Kondo, Manami

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Mizuno, Rie

× Mizuno, Rie

en Mizuno, Rie

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Shibuya, Shinichi

× Shibuya, Shinichi

en Shibuya, Shinichi

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Hashiba, Yoshiki

× Hashiba, Yoshiki

en Hashiba, Yoshiki

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Asada, Yoshimasa

× Asada, Yoshimasa

en Asada, Yoshimasa

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
権利情報Resource http://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
言語 en
キーワード
主題Scheme Other
主題 clomiphene
キーワード
主題Scheme Other
主題 pregnancy
キーワード
主題Scheme Other
主題 premature ovarian insufficiency
キーワード
主題Scheme Other
主題 relugolix
キーワード
主題Scheme Other
主題 oral gonadotropin-releasing hormone antagonist
内容記述
内容記述タイプ Abstract
内容記述 To the best of our knowledge, this is the first case of pregnancy with a healthy baby after treatment with an oral gonadotropin-releasing hormone (GnRH) antagonist in women with premature ovarian insufficiency. A 36-year-old female presented at our hospital after being diagnosed with premature ovarian insufficiency by a previous doctor. We administered clomiphene, human menopausal gonadotropin (hMG), and GnRH antagonist (injection) together with estrogen replacement for 11 cycles (27 months), but no follicular development was observed. When the oral GnRH antagonist (relugolix), which has recently become available, was used in the 12^th cycle, follicular growth of 13 mm was confirmed on the 14^th day of stimulation. After stimulation, the use of hMG and GnRH antagonist (injection) was continued, and a maturation trigger, human chorionic gonadotropin 10000 IU, was administered. Oocyte retrieval was performed successfully, intracytoplasmic sperm injection and frozen embryo transfer were performed, and fetal heartbeat was confirmed. The patient was admitted to the perinatal management facility. She delivered a healthy baby of 3,732 g via cesarean section at 41 weeks +2. This case shows the possibility of using an oral GnRH antagonist as an option for infertility treatment.
言語 en
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.86.2.333
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/862.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 86, 号 2, p. 333-340, 発行日 2024-05
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