| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2024-05-28 |
| タイトル |
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タイトル |
The effect of age on the relationship between body mass index and risks of incident stroke subtypes: The JPHC study |
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言語 |
en |
| 著者 |
Nuamah, Hanson Gabriel
Li, Yuanying
Yatsuya, Hiroshi
Yamagishi, Kazumasa
Saito, Isao
Kokubo, Yoshihiro
Muraki, Isao
Iso, Hiroyasu
Inoue, Manami
Tsugane, Shoichiro
Sawada, Norie
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
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|
権利情報 |
© 2024. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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言語 |
en |
| 内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Objective: The associations between body mass index (BMI) and stroke subtypes, particularly intracerebral hemorrhage, have not been consistent. Such inconsistencies may be due to differences in the age at which BMI was obtained. We examined the possible age modifications in the association between BMI and stroke risk. Materials and Methods: We followed 88,754 participants, aged 40–69 years at baseline (1990-1994), of the Japan Public Health Center-based prospective (JPHC) study for stroke incidence. BMI was obtained using self-reported body weight and height, which were categorized using the following cut-off points: 18.5, 21, 23, 25, 27.5, and 30 kg/m2. Time-dependent Cox proportional hazards models that updated BMI and covariates using 5- and 10-year questionnaire responses were used to estimate hazard ratios and 95 % confidence intervals. The analyses were stratified by age group (40–59 and ≥60 years) and the age of the individuals was updated. Results: During the median follow-up period of 19 years, we documented 4,690 strokes, including 2,781 ischemic strokes and 1,358 intracerebral hemorrhages. After adjusting for sex, age, smoking, alcohol consumption, leisure-time physical activity, history of hypertension, dyslipidemia, and diabetes mellitus, we observed a positive linear association between BMI and ischemic stroke (linear trend, p < 0.001) in both age groups (interaction p>0.05). In contrast, a curvilinear association between BMI and intracerebral hemorrhage was observed in both the middle (curvilinear trend, p=0.017) and the older group (curvilinear trend, p=0.098) (interaction p>0.05). Conclusion: BMI and stroke associations did not vary significantly with age, although the association may differ according to subtype. |
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言語 |
en |
| 出版者 |
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出版者 |
Elsevier |
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言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107486 |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
10523057 |
| 書誌情報 |
en : Journal of Stroke and Cerebrovascular Diseases
巻 33,
号 2,
p. 107486,
発行日 2024-02
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| ファイル公開日 |
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|
日付 |
2025-02-01 |
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日付タイプ |
Available |
NuamahHG.pdf (625 KB)
