| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2024-11-27 |
| タイトル |
|
|
タイトル |
Clinical characteristics and antimicrobial susceptibility of Eggerthella lenta infection over a 5-year trend at a university hospital in Japan |
|
言語 |
en |
| 著者 |
Mori, Nobuaki
Nakamura, Akiko
Hirai, Jun
Asai, Nobuhiro
Shibata, Yuichi
Takayama, Mina
Kawamoto, Yuzuka
Miyazaki, Narimi
Sakanashi, Daisuke
Ohno, Tomoko
Yamada, Atsuko
Suematsu, Hiroyuki
Koita, Isao
Chida, Sumie
Ohta, Toshiaki
Mikamo, Hiroshige
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
|
|
権利情報Resource |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |
|
言語 |
en |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Eggerthella lenta |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
antibiotic susceptibility |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
anaerobe |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
minimum inhibitory concentration |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
surgical intervention |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
Eggerthella lenta (E. lenta) is known to cause intra-abdominal and anaerobic bloodstream infections. However, clinical insights and information on antimicrobial susceptibility in E. lenta infections are limited. This study aimed to elucidate the clinical characteristics and antimicrobial susceptibility of E. lenta infections. Patients with E. lenta isolated from various specimens who presented at Aichi Medical University Hospital between January 2018 and December 2022 were included. Patient information was retrospectively collected from electronic medical records. Logistic regression analysis was conducted to identify risk factors for bloodstream infections. The antimicrobial susceptibility of various antimicrobial agents against isolated strains was investigated. During the study period, seventy cases were classified as infection cases. The median age of patients was 69 years (range: 15–100 years), and 48 (68.6%) were males. The most common site of infection was the lower digestive tract (54.3%). In 70.4% of cases, polymicrobial infections occurred. Community-acquired infection was a significant risk factor for bloodstream infection, with an odds ratio of 4.94 (95% confidence interval: 1.02–23.9). The 30-day mortality rate was 10.0%. Univariate analysis showed lower mortality in patients who underwent surgical intervention than in those who did not (42.9% vs 57.1%, p = 0.02). The proportion of minimal inhibitory concentrations (MICs) of ≥ 32 μg/mL for piperacillin-tazobactam was 6.3%. Additionally, the proportions of MICs of ≥ 8 μg/mL for imipenem and meropenem were 1.4% and 0%, respectively. E. lenta should be considered when blood cultures yield gram-positive rods in community-acquired intra-abdominal infections. Effective treatment involves both antimicrobial agents and surgical interventions. |
|
言語 |
en |
| 出版者 |
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|
出版者 |
Nagoya University Graduate School of Medicine, School of Medicine |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
|
|
ID登録 |
10.18999/nagjms.86.4.683 |
|
ID登録タイプ |
JaLC |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/864.html |
| 収録物識別子 |
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|
収録物識別子タイプ |
PISSN |
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収録物識別子 |
0027-7622 |
| 収録物識別子 |
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|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2186-3326 |
| 書誌情報 |
en : Nagoya Journal of Medical Science
巻 86,
号 4,
p. 683-692,
発行日 2024-11
|
12_Mori.pdf (447.8 KB)
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