| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2024-12-10 |
| タイトル |
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タイトル |
Frailty Index Based on Common Laboratory Tests for Patients Starting Home-Based Medical Care |
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言語 |
en |
| 著者 |
Nakashima, Hirotaka
Watanabe, Kazuhisa
Komiya, Hitoshi
Fujisawa, Chisato
Yamada, Yosuke
Sakai, Tomomichi
Tajima, Tomihiko
Umegaki, Hiroyuki
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
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|
権利情報 |
© 2024. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
言語 |
en |
| 内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Objectives: To determine whether a Frailty Index based on laboratory tests (FI-lab) is associated with clinical outcomes independently of a standard nonlaboratory Frailty Index (FI-clinical) in older patients starting home-based medical care. Design: Secondary analysis of data from a multicenter prospective cohort study. Setting and Participants: Patients aged ≥65 years who were starting home-based medical care services provided by doctors and nurses at Nagoya, Japan. Methods: We calculated FI-lab (proportion of abnormal results out of 25 commonly tested laboratory parameters) and FI-clinical using 42 items based on data obtained at enrollment. The primary outcome was mortality within 2 years after starting home-based medical care. A sensitivity analysis was also conducted with 1-year mortality as the outcome. Other outcomes included hospitalization and nursing home admission within 2 years. Results: In total, 188 patients (mean age 79.9 ± 10.2 years, 57.5% male) were included. The median FI-lab was 0.40 [interquartile range (IQR) 0.29-0.50] and the median FI-clinical was 0.32 (IQR 0.24-0.43). Sixty-nine patients (36.7%) died within 2 years of starting home-based medical care. A Cox proportional hazards regression analysis including age, sex, FI-lab, and FI-clinical as independent variables revealed that FI-lab was associated with 2-year mortality independently of FI-clinical [FI-lab per 0.1 unit, odds ratio (OR) 1.49, 95% CI 1.25-1.77; FI-clinical per 0.1 unit, OR 1.13, 95% CI 0.90-1.41]. The sensitivity analysis showed similar results for 1-year mortality. Neither FI-lab nor FI-clinical was associated with hospitalization or nursing home admission within 2 years. Conclusions and Implications: FI-lab was associated with 2-year mortality in patients starting home-based medical care, independently of FI-clinical, and may be useful for risk assessment in this population. Studies with larger sample sizes are needed. |
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言語 |
en |
| 出版者 |
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出版者 |
Elsevier |
|
言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.jamda.2024.105114 |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
15258610 |
| 書誌情報 |
en : Journal of the American Medical Directors Association
巻 25,
号 9,
p. 105114,
発行日 2024-09
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| ファイル公開日 |
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日付 |
2025-09-01 |
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日付タイプ |
Available |
UnblindedManuscript240517.pdf (611 KB)
