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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Predicting early rebleeding and mortality after endoscopic hemostasis of esophagogastric varices: Diagnostic performance of aspartate aminotransferase‐to‐platelet ratio index and model for end‐stage liver disease‐Na score

http://hdl.handle.net/2237/0002011781
http://hdl.handle.net/2237/0002011781
c5dbbcdc-f735-45ab-8816-c2d5f7aa35b3
名前 / ファイル ライセンス アクション
JHBPS-2024-0147.R2_Proof_hi.pdf JHBPS-2024-0147.R2_Proof_hi.pdf (784 KB)
アイテムタイプ itemtype_ver1(1)
公開日 2024-12-10
タイトル
タイトル Predicting early rebleeding and mortality after endoscopic hemostasis of esophagogastric varices: Diagnostic performance of aspartate aminotransferase‐to‐platelet ratio index and model for end‐stage liver disease‐Na score
言語 en
著者 Yokoyama, Shinya

× Yokoyama, Shinya

en Yokoyama, Shinya

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Honda, Takashi

× Honda, Takashi

en Honda, Takashi

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Ishizu, Yoji

× Ishizu, Yoji

en Ishizu, Yoji

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Imai, Norihiro

× Imai, Norihiro

en Imai, Norihiro

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Ito, Takanori

× Ito, Takanori

en Ito, Takanori

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Yamamoto, Kenta

× Yamamoto, Kenta

en Yamamoto, Kenta

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Mizuno, Kazuyuki

× Mizuno, Kazuyuki

en Mizuno, Kazuyuki

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Nakamura, Masanao

× Nakamura, Masanao

en Nakamura, Masanao

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Kawashima, Hiroki

× Kawashima, Hiroki

en Kawashima, Hiroki

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
権利情報 "This is the peer reviewed version of the following article: [Yokoyama S, Honda T, Ishizu Y, Imai N, Ito T, Yamamoto K, et al. Predicting early rebleeding and mortality after endoscopic hemostasis of esophagogastric varices: Diagnostic performance of aspartate aminotransferase-to-platelet ratio index and model for end-stage liver disease-Na score. J Hepatobiliary Pancreat Sci. 2024; 31: 830–839. https://doi.org/10.1002/jhbp.12057], which has been published in final form at [https://doi.org/10.1002/jhbp.12057]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited."
言語 en
内容記述
内容記述タイプ Abstract
内容記述 Background: Endoscopic variceal ligation and sclerotherapy are recommended for esophagogastric variceal bleeding (EGVB) in cirrhosis but can be complicated by early rebleeding and death. This study aimed to identify noninvasive markers accurately predicting early rebleeding and mortality after endoscopic hemostasis for EGVB. Methods: Among 116 patients with endoscopically confirmed EGVB and endoscopic hemostasis, various noninvasive markers were calculated, and their predictive accuracy was compared by receiver-operating characteristic curve analysis. Endpoints included 5-day rebleeding, 5-day mortality, 6-week rebleeding, and 6-week mortality. Results: The median age was 63 years. Child-Pugh class B and C patients accounted for 40.5% and 34.5%, respectively. Only the aspartate aminotransferase-to-platelet ratio index (APRI) significantly predicted 5-day rebleeding, with an area under the curve (AUC) of 0.777 (95% confidence interval [CI]: 0.537–1). The model for end-stage liver disease-Na (MELD-Na) score showed good predictive accuracy for 5-day mortality (AUC: 0.839, 95% CI: 0.681–0.997), 6-week rebleeding (AUC: 0.797, 95% CI: 0.663–0.932), and 6-week mortality (AUC: 0.888, 95% CI: 0.797–0.979). Conclusions: Patients with cirrhosis with a high APRI and MELD-Na score were at high risk of early rebleeding and death after EGVB. Allocating appropriate monitoring and care for those patients is necessary.
言語 en
出版者
出版者 Wiley
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1002/jhbp.12057
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 1868-6974
書誌情報 en : Journal of Hepato-Biliary-Pancreatic Sciences

巻 31, 号 11, p. 830-839, 発行日 2024-11
ファイル公開日
日付 2025-11-01
日付タイプ Available
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