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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

The impact of goal-directed prehabilitation therapy on functional capacity in patients undergoing hepatobiliary and pancreatic surgery: A randomized clinical trial

http://hdl.handle.net/2237/0002011808
http://hdl.handle.net/2237/0002011808
fdfcb87a-ba36-4c78-8319-1bcb903348f7
名前 / ファイル ライセンス アクション
GOLD_study_manuscript_revision_to_Surgery.pdf GOLD_study_manuscript_revision_to_Surgery.pdf (1.6 MB)
アイテムタイプ itemtype_ver1(1)
公開日 2024-12-16
タイトル
タイトル The impact of goal-directed prehabilitation therapy on functional capacity in patients undergoing hepatobiliary and pancreatic surgery: A randomized clinical trial
言語 en
著者 Mizuno, Yota

× Mizuno, Yota

en Mizuno, Yota

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Yokoyama, Yukihiro

× Yokoyama, Yukihiro

en Yokoyama, Yukihiro

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Nakajima, Hiroki

× Nakajima, Hiroki

en Nakajima, Hiroki

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Inoue, Takayuki

× Inoue, Takayuki

en Inoue, Takayuki

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Tanaka, Shinya

× Tanaka, Shinya

en Tanaka, Shinya

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Nagaya, Motoki

× Nagaya, Motoki

en Nagaya, Motoki

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Inokawa, Yoshikuni

× Inokawa, Yoshikuni

en Inokawa, Yoshikuni

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Ando, Masahiko

× Ando, Masahiko

en Ando, Masahiko

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Nishida, Yoshihiro

× Nishida, Yoshihiro

en Nishida, Yoshihiro

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Ebata, Tomoki

× Ebata, Tomoki

en Ebata, Tomoki

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
権利情報 © 2024. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
言語 en
内容記述
内容記述タイプ Abstract
内容記述 Background: Emerging evidence has supported the idea that goal-directed prehabilitation is a promising approach to boost functional capacity in preoperative patients. However, its usefulness has not been tested in the hepatobiliary and pancreatic fields. The objective of this trial was to investigate the efficacy of goal-directed prehabilitation for improving functional capacity in patients who were planned to undergo major hepatobiliary and pancreatic operations. Methods: This assessor-blinded, parallel-arm, randomized clinical trial recruited patients who were scheduled for major hepatobiliary and pancreatic surgeries for malignancy. Patients were randomly allocated into the step goal-directed prehabilitation group as the test group and into the conventional prehabilitation group as the control group. Patients in the goal-directed prehabilitation group participated in a walking prehabilitation program with an intergrading goal of the step count. Patients in the conventional prehabilitation group received standard physical and nutritional prehabilitation. The primary outcome was change in the 6-minute walking distance, which ranged from the time before starting prehabilitation (baseline) to the time after completing prehabilitation (immediately before surgery). Results: Among 180 randomized patients, 144 patients were included in the primary analysis (73 patients in the conventional prehabilitation group and 71 patients in the goal-directed prehabilitation group). The mean change in the 6-minute walking distance was 27 meters in the conventional prehabilitation group and 31 meters in the goal-directed prehabilitation group (P = .633). Conclusion: In patients undergoing major hepatobiliary and pancreatic surgeries for malignancies, a goal-directed prehabilitation program did not result in a significantly greater increase in functional capacity than did conventional prehabilitation. Registration number: UMIN000038791 (https://www.umin.ac.jp/ ).
言語 en
出版者
出版者 Elsevier
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.surg.2024.04.024
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 00396060
書誌情報 en : Surgery

巻 176, 号 2, p. 252-258, 発行日 2024-08
ファイル公開日
日付 2025-08-01
日付タイプ Available
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