| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2025-01-22 |
| タイトル |
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タイトル |
Aging in females has minimal effect on changes in celiac artery blood flow during dynamic light-intensity exercise |
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言語 |
en |
| 著者 |
Shiozawa, Kana
Saito, Mitsuru
Lee, Jordan B.
Seo, Natsuki
Kondo, Haruna
Kashima, Hideaki
Yamaoka Endo, Masako
Ishida, Koji
Millar, Philip J.
Katayama, Keisho
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Blood flow to the active muscles and arterial blood pressure (ABP) increase during dynamic exercise, whereas blood flow to inactive organs (e.g., splanchnic organs and inactive limbs) declines. Aging leads to exaggerated ABP responses to exercise in females, but whether this is related to greater splanchnic vasoconstriction is unknown. This study sought to clarify the effect of aging in females on celiac artery blood flow during dynamic light-intensity exercise. Twelve healthy young females (YF: 20 ± 2 yr, mean ± SD) and 12 healthy older females (OF: 71 ± 4 yr) performed dynamic knee-extension and knee-flexion exercises at 30% of heart rate reserve for 4 min. The absolute changes from baseline (Δ) for mean arterial blood pressure (MAP), celiac artery mean blood flow (celMBF), and celiac vascular conductance (celVC) during exercise were calculated. ABP was measured using an automated sphygmomanometer, and celMBF was recorded by Doppler ultrasonography. The increase in MAP during exercise was greater in OF than in YF (YF: +14 ± 7 mmHg, OF: +24 ± 13 mmHg, P = 0.028). The celMBF decreased during exercise in both groups, but there was no significant difference in the response between YF and OF (YF: −93.0 ± 66.1 mL/min, OF: −89.6 ± 64.0 mL/min, P = 0.951). The celVC also decreased during exercise and remained lower than baseline during exercise. However, the response was not different between YF and OF (YF: −1.8 ± 1.0 mL/min/mmHg, OF: −1.5 ± 0.6 mL/min/mmHg, P = 0.517). These results demonstrate that aging in females has minimal influence on splanchnic artery hemodynamic responses during dynamic light-intensity exercise, suggesting that exaggerated ABP responses during exercise in OF are not due to greater splanchnic vasoconstriction. |
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言語 |
en |
| 出版者 |
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出版者 |
American Physiological Society |
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言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1152/ajpregu.00012.2024 |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0363-6119 |
| 書誌情報 |
en : American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
巻 327,
号 1,
p. R14-R24,
発行日 2024-07
|
Shiozawa_et_al_AJP_Reg_2024_Accepted_version.pdf (953 KB)
