| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2025-06-12 |
| タイトル |
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タイトル |
Nanoparticle formation of β-carotene by mixing supercritical carbon dioxide antisolvent with liquefied dimethyl ether feed solution using swirl mixer |
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言語 |
en |
| 著者 |
Mei, Li
Kanda, Hideki
Zhu, Li
Wang, Tao
Yamamoto, Tetsuya
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| アクセス権 |
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アクセス権 |
embargoed access |
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アクセス権URI |
http://purl.org/coar/access_right/c_f1cf |
| 権利 |
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権利情報 |
© 2025. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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言語 |
en |
| 内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
The production of β-carotene nanoparticles using non-toxic and environmentally-friendly liquefied dimethyl ether (DME) via a supercritical antisolvent (SAS) process, which produces no residue, is a major challenge in food processes. Preparations of nanoparticles have previously been conducted with toxic organic feed solvents. In this work, β-carotene was micronized with two feed solutions, liquefied DME and ethyl acetate, using a swirl mixer mixing in a turbulent field by the SAS method for comparison. The effects of operating pressure, temperature, and solution flow rate were investigated on the size of nanoparticles. Field-emission-scanning electron microscopy (FE-SEM) images showed that dispersed β-carotene nanoparticles, 43.9 nm in size, were successfully prepared at 40 °C and 8 MPa, and no residual DME was present in the nanoparticles. Using an ethyl acetate solution to precipitate β-carotene at 40 °C and 10 MPa and successfully obtained nanoparticles 62.12 nm in size. Compared to the previous study (12 MPa, normal nozzle), the smallest β-carotene particles precipitated from the optimal conditions of DME and ethyl acetate, respectively, were obtained at lower pressures and smaller particles with the swirl mixer. X-ray diffraction (XRD) and differential thermal analysis (DTA) confirmed that the obtained nanoparticles were amorphous. By contrast, residual ethyl acetate solution was present in the nanoparticles precipitated from ethyl acetate; this phenomenon was confirmed using Fourier transform infrared spectroscopy (FT-IR) and gas chromatography-mass spectrometry (GC–MS). |
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言語 |
en |
| 出版者 |
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出版者 |
Elsevier |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.apt.2025.104871 |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0921-8831 |
| 書誌情報 |
en : Advanced Powder Technology
巻 36,
号 6,
p. 104871,
発行日 2025-06
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| ファイル公開日 |
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日付 |
2027-06-01 |
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日付タイプ |
Available |
2_Rev2_Mei_Swirl_mixer.pdf (4 MB)
