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  1. C100 医学部/医学系研究科
  2. C100b 刊行物
  3. Nagoya journal of medical science
  4. 87(3)

Incidence and risk factors of cerebrospinal fluid leakage related complications after spinal intradural tumor resection

https://doi.org/10.18999/nagjms.87.3.521
https://doi.org/10.18999/nagjms.87.3.521
56ca8820-95ae-474f-b795-753a37c239ea
名前 / ファイル ライセンス アクション
12_Nakashima.pdf 12_Nakashima.pdf (433.1 KB)
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アイテムタイプ itemtype_ver1(1)
公開日 2024-09-09
タイトル
タイトル Incidence and risk factors of cerebrospinal fluid leakage related complications after spinal intradural tumor resection
言語 en
著者 Nakashima, Hiroaki

× Nakashima, Hiroaki

en Nakashima, Hiroaki

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Ota, Kyotaro

× Ota, Kyotaro

en Ota, Kyotaro

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Ito, Sadayuki

× Ito, Sadayuki

en Ito, Sadayuki

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Segi, Naoki

× Segi, Naoki

en Segi, Naoki

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Ouchida, Jun

× Ouchida, Jun

en Ouchida, Jun

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Yamauchi, Ippei

× Yamauchi, Ippei

en Yamauchi, Ippei

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Ode, Yukihito

× Ode, Yukihito

en Ode, Yukihito

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Imagama, Shiro

× Imagama, Shiro

en Imagama, Shiro

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
権利情報Resource http://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
言語 en
キーワード
主題Scheme Other
主題 cerebrospinal fluid leakage
キーワード
主題Scheme Other
主題 intradural tumor
キーワード
主題Scheme Other
主題 postoperative complications
キーワード
主題Scheme Other
主題 MRI evaluation
キーワード
主題Scheme Other
主題 risk factors
内容記述
内容記述タイプ Abstract
内容記述 Cerebrospinal fluid (CSF) leakage is a common and serious complication of spinal surgery, particularly after intradural tumor resection. CSF leakage can lead to debilitating headaches, neurological deficits, and other symptoms, with an incidence rate of 0.3%–16%. This study aimed to investigate the incidence, risk factors, and outcomes of CSF-related complications in patients who underwent spinal intradural tumor surgery. This was a retrospective cohort study including 102 patients who underwent resection of intradural tumors, including ependymomas, astrocytomas, and meningiomas. Data were collected, including patient demographics, surgical details, and postoperative outcomes. The extent of CSF accumulation was evaluated using magnetic resonance imaging (MRI) findings. Statistical analyses were performed to identify risk factors for symptomatic CSF leakage. Postoperative CSF accumulation was observed in 94.1% of patients. Among them, 28.1% experienced symptomatic complications, such as severe headache (20.8%), unexplained fever (6.3%), and CSF leakage (3.1%). Patients with larger CSF accumulation, particularly subcutaneous accumulation, had a significantly higher incidence of symptomatic complications, with the highest rate observed in subfascial accumulation cases (P = 0.0002). Symptomatic patients did not show significant differences in age, sex, surgical level, drainage duration, or blood loss compared to asymptomatic patients. Additionally, the use of artificial dura mater did not significantly affect symptomatic outcomes. Predicting the occurrence of symptoms based on preoperative and surgical factors remains challenging. However, patients with subfascial CSF accumulation were more likely to develop symptoms, highlighting the necessity of confirming CSF accumulation using MRI for appropriate postoperative management.
言語 en
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.87.3.521
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/873.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 87, 号 3, p. 521-527, 発行日 2025-08
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