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  1. C100 医学部/医学系研究科
  2. C100b 刊行物
  3. Nagoya journal of medical science
  4. 87(3)

Clinical outcomes of posterior lumbar interbody fusion in chronic renal failure patients on hemodialysis

https://doi.org/10.18999/nagjms.87.3.528
https://doi.org/10.18999/nagjms.87.3.528
c0b4f4a9-8984-4876-a955-e9d6e030cf52
名前 / ファイル ライセンス アクション
13_Nakashima.pdf 13_Nakashima.pdf (4.5 MB)
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アイテムタイプ itemtype_ver1(1)
公開日 2024-09-09
タイトル
タイトル Clinical outcomes of posterior lumbar interbody fusion in chronic renal failure patients on hemodialysis
言語 en
著者 Nakashima, Hiroaki

× Nakashima, Hiroaki

en Nakashima, Hiroaki

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Ito, Sadayuki

× Ito, Sadayuki

en Ito, Sadayuki

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Segi, Naoki

× Segi, Naoki

en Segi, Naoki

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Ouchida, Jun

× Ouchida, Jun

en Ouchida, Jun

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Yamauchi, Ippei

× Yamauchi, Ippei

en Yamauchi, Ippei

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Sato, Koji

× Sato, Koji

en Sato, Koji

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Imagama, Shiro

× Imagama, Shiro

en Imagama, Shiro

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
権利情報Resource http://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
言語 en
キーワード
主題Scheme Other
主題 adjacent segment disease
キーワード
主題Scheme Other
主題 bone fragility
キーワード
主題Scheme Other
主題 chronic renal failure
キーワード
主題Scheme Other
主題 destructive spondyloarthropathy
キーワード
主題Scheme Other
主題 hemodialysis
内容記述
内容記述タイプ Abstract
内容記述 Chronic kidney disease (CKD) and its treatment with hemodialysis (HD) pose unique challenges for spinal surgery due to complications such as destructive spondyloarthropathy (DSA). This study retrospectively compared the surgical outcomes of posterior lumbar interbody fusion (PLIF) between 48 HD patients and 57 non-HD controls. Patients with tumors, infections, prior spinal surgery, or severe osteoporosis were excluded. HD patients had a mean dialysis duration of 16.2 years, while controls were treated for degenerative lumbar conditions. HD patients exhibited significantly higher intraoperative blood loss (415.8 ± 231.7 mL vs 293.4 ± 57.3 mL, P < 0.001) and lower 2-year bony fusion rates (72.9% vs 94.7%, P = 0.008). Pseudoarthrosis and adjacent segment disease (ASD) were more common in the HD group, necessitating reoperation in five cases versus one in controls. Neurological recovery at 2 years was worse in the HD group, with a mean Japanese Orthopaedic Association score of 19.6 ± 4.3 compared to 26.5 ± 2.2 in controls (P < 0.01). Despite facilitating initial neurological recovery, PLIF outcomes in HD patients were compromised by greater complication rates, including pseudoarthrosis and ASD. Thus, PLIF facilitates early neurological improvement in HD patients, but long-term functional outcomes are compromised due to higher rates of pseudoarthrosis and ASD, necessitating careful long-term management. Strategies minimizing mechanical stress and maintaining spinal alignment could further support long-term patient recovery.
言語 en
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.87.3.528
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/873.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 87, 号 3, p. 528-537, 発行日 2025-08
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