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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Sleep Deprivation Elevates Resting and Exercise Blood Pressures and Augments Pressor Response at Exercise Onset

http://hdl.handle.net/2237/0002013695
http://hdl.handle.net/2237/0002013695
2b1ecfd0-2c2c-4020-8cf1-622824975a44
名前 / ファイル ライセンス アクション
Hori_et_al_MedSciSportsExerc_2025.pdf Hori_et_al_MedSciSportsExerc_2025.pdf (1.4 MB)
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アイテムタイプ itemtype_ver1(1)
公開日 2025-12-03
タイトル
タイトル Sleep Deprivation Elevates Resting and Exercise Blood Pressures and Augments Pressor Response at Exercise Onset
言語 en
著者 HORI, AMANE

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en HORI, AMANE

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SU, XIN

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en SU, XIN

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SAGASAKI, SHOTA

× SAGASAKI, SHOTA

en SAGASAKI, SHOTA

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SAITO, RYUJI

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en SAITO, RYUJI

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SUIJO, KENICHI

× SUIJO, KENICHI

en SUIJO, KENICHI

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MIYATA, SEIKO

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en MIYATA, SEIKO

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HASEGAWA, DAISUKE

× HASEGAWA, DAISUKE

en HASEGAWA, DAISUKE

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MIZUNO, MASAKI

× MIZUNO, MASAKI

en MIZUNO, MASAKI

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HOTTA, NORIO

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en HOTTA, NORIO

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アクセス権
アクセス権 embargoed access
アクセス権URI http://purl.org/coar/access_right/c_f1cf
権利
権利情報 "This is a non-final version of an article published in final form in (HORI, AMANE; SU, XIN; SAGASAKI, SHOTA; SAITO, RYUJI; SUIJO, KENICHI; MIYATA, SEIKO; HASEGAWA, DAISUKE; MIZUNO, MASAKI; HOTTA, NORIO. Sleep Deprivation Elevates Resting and Exercise Blood Pressures and Augments Pressor Response at Exercise Onset. Medicine & Science in Sports & Exercise 57(5):p 996-1007, May 2025. DOI: 10.1249/MSS.0000000000003640)."
言語 en
内容記述
内容記述タイプ Abstract
内容記述 Purpose: Sleep deprivation and elevated blood pressure (BP) increase the risk of cardiovascular diseases. However, the effects of sleep deprivation on BP response, especially at exercise onset, remain unclear. We aimed to elucidate the effects of experimental sleep deprivation (ESD) on resting and exercise BPs, including that at exercise onset, and investigate whether a nighttime nap during ESD changes the ESD-altered BP. Methods: Twelve healthy young men underwent 2-min submaximal isometric elbow flexion (IEF) exercise to measure BP after 7 d of normal sleep (control trial), 24-h ESD (ESD trial), and ESD with a 2-h nighttime nap (ESD + NAP trial), which were randomly performed. Results: ESD significantly elevated the mean arterial pressure (MAP) at rest (85.8 ± 8.0 to 93.3 ± 5.1 mm Hg, P = 0.003) and at the last minute of IEF (116.9 ± 13.0 to 126.2 ± 11.8 mm Hg, P = 0.003) compared with that observed in the control trial. At IEF onset (the initial 15 s), ESD significantly elevated the MAP (88.7 ± 12.6 to 103.1 ± 8.8 mm Hg, P < 0.001) and augmented the MAP responsiveness from baseline, compared with that observed in the control trial (Δ2.9 ± 11.4 to Δ9.8 ± 6.6 mm Hg, P = 0.017). The MAP responsiveness in the ESD + NAP trial (Δ7.3 ± 5.2 mm Hg) was not significantly different from that in the control trial (P = 0.165) and the ESD trial (P = 0.129). Conclusions: ESD significantly elevated both resting BP and the BP during submaximal isometric exercise and significantly augmented the initial pressor response to the exercise. A 2-h nighttime nap during ESD appears to be insufficient to completely attenuate ESD-induced augmented pressor responses.
言語 en
出版者
出版者 Wolters Kluwer Health
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1249/MSS.0000000000003640
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0195-9131
書誌情報 en : Medicine and science in sports and exercise

巻 57, 号 5, p. 996-1007, 発行日 2025-05
ファイル公開日
日付 2026-05-01
日付タイプ Available
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