| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2025-12-17 |
| タイトル |
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|
タイトル |
Antimicrobial use in pediatric patients: a subgroup analysis of the 2020 point prevalence survey in Aichi, Japan |
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言語 |
en |
| 著者 |
Morioka, Hiroshi
Ito, Kenta
Koizumi, Yusuke
Okudaira, Masami
Tomita, Yuka
Tsuji, Takeshi
Akita, Kenji
Watariguchi, Toshitaka
Oka, Keisuke
Watamoto, Koichi
Kato, Hiroki
Ishihara, Masamitsu
Yokota, Manabu
Ito, Yuji
Mutoh, Yoshikazu
Nagaoka, Masatoshi
Iwata, Susumu
Nozaki, Yasuhiro
Hamada, Hiroshi
Kojima, Yumi
Kawasaki, Shohei
Hasegawa, Chihiro
Shimizu, Junichi
Yagi, Tetsuya
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| アクセス権 |
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アクセス権 |
embargoed access |
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アクセス権URI |
http://purl.org/coar/access_right/c_f1cf |
| 権利 |
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|
権利情報 |
© 2025. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
言語 |
en |
| 内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: Establishing the precise epidemiology of antimicrobial use (AMU) is essential to promote antimicrobial stewardship. However, data on AMU for pediatric inpatients in Japanese hospitals are lacking. In this study, we performed a subgroup analysis focusing on pediatric patients from a point prevalence survey. Methods: A multicenter point prevalence survey was conducted in Aichi Prefecture in 2020. This subgroup analysis included pediatric patients (≦18 years old) and assessed AMU and their indications: community-acquired infections (CAIs), healthcare-associated infections (HAIs), medical prophylaxis (MP), and surgical prophylaxis (SP). Details of infections and interventions by the antimicrobial stewardship teams (AST) were also surveyed. Results: Of the 736 patients from 23 hospitals included in this study, 241 patients (32.7 %, 95 % confidence interval [95 % CI]: 29.4–36.3) received a total of 399 antimicrobials. The prevalence of HAI was 6.0 % (95 % CI: 4.4–7.9). The number of antimicrobials administered per 100 patients ranged from 24.1 in small hospitals to 109.6 in university hospitals. CAI treatment was the most common indication in community hospitals, SP in specific centers, and MP in university hospitals. The most commonly prescribed antimicrobials were cefotaxime for CAI, meropenem for HAI, trimethoprim-sulfamethoxazole for MP, and cefazolin for SP. A total of 78 CAIs and 46 HAIs were identified, with AST intervention rates of 2.5 % and 34.8 %, respectively. Conclusion: This subgroup analysis provides the first demographic data on AMU among pediatric inpatients at Japanese hospitals. The distinct distribution of AMU suggests that different approaches are necessary to promote antimicrobial stewardship in hospital settings. |
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言語 |
en |
| 出版者 |
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出版者 |
Elsevier |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1016/j.jiac.2025.102804 |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1341-321X |
| 書誌情報 |
en : Journal of Infection and Chemotherapy
巻 31,
号 10,
p. 102804,
発行日 2025-10
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| ファイル公開日 |
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|
日付 |
2026-10-01 |
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日付タイプ |
Available |