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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Antimicrobial use in pediatric patients: a subgroup analysis of the 2020 point prevalence survey in Aichi, Japan

http://hdl.handle.net/2237/0002013734
http://hdl.handle.net/2237/0002013734
9fe08868-eefe-4f38-bc4a-fb12267d8f58
名前 / ファイル ライセンス アクション
Pedi_20250814.pdf Pedi_20250814.pdf (462 KB)
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Pedi_PPS_Fig_1a.pdf Pedi_PPS_Fig_1a.pdf (34 KB)
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Figure_1b_20250904_1.1.pdf Figure_1b_20250904_1.1.pdf (52 KB)
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Fig_2_Pedi_PPS.pdf Fig_2_Pedi_PPS.pdf (62 KB)
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New_Fig_3.pdf New_Fig_3.pdf (34 KB)
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Supplementary_data.zip Supplementary_data.zip (56 KB)
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アイテムタイプ itemtype_ver1(1)
公開日 2025-12-17
タイトル
タイトル Antimicrobial use in pediatric patients: a subgroup analysis of the 2020 point prevalence survey in Aichi, Japan
言語 en
著者 Morioka, Hiroshi

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en Morioka, Hiroshi

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Ito, Kenta

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en Ito, Kenta

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Koizumi, Yusuke

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en Koizumi, Yusuke

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Okudaira, Masami

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en Okudaira, Masami

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Tomita, Yuka

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Tsuji, Takeshi

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en Tsuji, Takeshi

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Akita, Kenji

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en Akita, Kenji

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Watariguchi, Toshitaka

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Oka, Keisuke

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en Oka, Keisuke

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Watamoto, Koichi

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en Watamoto, Koichi

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Kato, Hiroki

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en Kato, Hiroki

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Ishihara, Masamitsu

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en Ishihara, Masamitsu

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Yokota, Manabu

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en Yokota, Manabu

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Ito, Yuji

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Mutoh, Yoshikazu

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Nagaoka, Masatoshi

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Iwata, Susumu

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en Iwata, Susumu

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Nozaki, Yasuhiro

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en Nozaki, Yasuhiro

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Hamada, Hiroshi

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Kojima, Yumi

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Kawasaki, Shohei

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Hasegawa, Chihiro

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Shimizu, Junichi

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Yagi, Tetsuya

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アクセス権
アクセス権 embargoed access
アクセス権URI http://purl.org/coar/access_right/c_f1cf
権利
権利情報 © 2025. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
言語 en
内容記述
内容記述タイプ Abstract
内容記述 Background: Establishing the precise epidemiology of antimicrobial use (AMU) is essential to promote antimicrobial stewardship. However, data on AMU for pediatric inpatients in Japanese hospitals are lacking. In this study, we performed a subgroup analysis focusing on pediatric patients from a point prevalence survey. Methods: A multicenter point prevalence survey was conducted in Aichi Prefecture in 2020. This subgroup analysis included pediatric patients (≦18 years old) and assessed AMU and their indications: community-acquired infections (CAIs), healthcare-associated infections (HAIs), medical prophylaxis (MP), and surgical prophylaxis (SP). Details of infections and interventions by the antimicrobial stewardship teams (AST) were also surveyed. Results: Of the 736 patients from 23 hospitals included in this study, 241 patients (32.7 %, 95 % confidence interval [95 % CI]: 29.4–36.3) received a total of 399 antimicrobials. The prevalence of HAI was 6.0 % (95 % CI: 4.4–7.9). The number of antimicrobials administered per 100 patients ranged from 24.1 in small hospitals to 109.6 in university hospitals. CAI treatment was the most common indication in community hospitals, SP in specific centers, and MP in university hospitals. The most commonly prescribed antimicrobials were cefotaxime for CAI, meropenem for HAI, trimethoprim-sulfamethoxazole for MP, and cefazolin for SP. A total of 78 CAIs and 46 HAIs were identified, with AST intervention rates of 2.5 % and 34.8 %, respectively. Conclusion: This subgroup analysis provides the first demographic data on AMU among pediatric inpatients at Japanese hospitals. The distinct distribution of AMU suggests that different approaches are necessary to promote antimicrobial stewardship in hospital settings.
言語 en
出版者
出版者 Elsevier
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.jiac.2025.102804
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 1341-321X
書誌情報 en : Journal of Infection and Chemotherapy

巻 31, 号 10, p. 102804, 発行日 2025-10
ファイル公開日
日付 2026-10-01
日付タイプ Available
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