| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2025-12-19 |
| タイトル |
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|
タイトル |
Lymph node density as prognostic factor in regional recurrent or residual head and neck cancer |
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言語 |
en |
| 著者 |
Goto, Seiya
Suzuki, Hidenori
Beppu, Shintaro
Nishikawa, Daisuke
Sawabe, Michi
Terada, Hoshino
Hanai, Nobuhiro
Sone, Michihiko
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| アクセス権 |
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|
アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
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|
権利情報 |
This is an Accepted Manuscript of an article published by Taylor & Francis Group in ACTA OTO-LARYNGOLOGICA on 29/11/2024, available at: https://doi.org/10.1080/00016489.2024.2432505 |
|
言語 |
en |
| 内容記述 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Prognostic factors from neck dissection for regional recurrent or residual head and neck cancer remain undetermined. Aims/objectives: We studied whether continuous variables from pathologic lymph nodes of salvage neck dissection could estimate survival outcomes in patients with head and neck squamous cell carcinomas (HNSCC). Materials and methods: Pathologic continuous variables from neck dissection without primary tumor resection in 184 patients with HNSCC were retrospectively evaluated. Cutoff values from both lymph node density (LND) and log odds of positive lymph nodes (LODDS) as the variables were applied to death estimation. Uni-/multivariate survival analyses adjusting for pathologic N classification and extranodal extension were evaluated by log-rank test or Cox’s proportional hazard model, respectively. Results: LND ≥ 0.14 and LODDS ≥ −1.72 were significantly related to univariate shorter survival outcomes. Multivariate analysis indicated a significant association between LND ≥ 0.14 and shorter overall (hazard ratio [HR] = 2.16, 95% confidence interval [CI] = 1.30–3.58), local recurrence-free (HR = 2.34, 95% CI = 1.06–5.16), regional recurrence-free (HR = 2.32, 95% CI = 1.27–4.25), and distant metastasis-free survival (HR = 2.17, 95% CI = 1.31–3.61). Conclusions and significance: Based on the obtained results, increased LND was a poor prognostic factor following salvage neck dissection. |
|
言語 |
en |
| 内容記述 |
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内容記述タイプ |
Other |
|
内容記述 |
Published online: 29 Nov 2024 |
|
言語 |
en |
| 出版者 |
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|
出版者 |
Taylor & Francis |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1080/00016489.2024.2432505 |
| 収録物識別子 |
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|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0001-6489 |
| 書誌情報 |
en : ACTA OTO-LARYNGOLOGICA
巻 145,
号 1,
p. 81-87,
発行日 2025
|
manuscript_R1-with_author_details.pdf (345 KB)
