| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2026-02-27 |
| タイトル |
|
|
タイトル |
Surgical outcomes and long-term prognosis of patients with tracheobronchial adenoid cystic carcinoma |
|
言語 |
en |
| 著者 |
Kawasumi, Yuta
Nakamura, Shota
Huang, Heng
Imamura, Yoshito
Okado, Shoji
Nomata, Yuji
Watanabe, Hiroki
Kadomatsu, Yuka
Ueno, Harushi
Kato, Taketo
Mizuno, Tetsuya
Chen-Yoshikawa, Toyofumi Fengshi
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
|
|
権利情報Resource |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |
|
言語 |
en |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
adenoid cystic carcinoma |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
carinal resection |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
tracheobronchial tumor |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Tracheobronchial adenoid cystic carcinoma (ACC) is a rare malignant disease of the central airways. Complete resection is the primary goal for this tumor; however, it remains challenging due to the complexity of reconstruction, tumor submucosal spread, and the risk of dehiscence. Conversely, tracheobronchial ACC has relatively favorable long-term outcomes due to its indolent growth. Due to the rarity of this tumor, a clear treatment guideline has yet to be established. This study aimed to evaluate treatment strategies, perioperative outcomes, and long-term prognosis of tracheobronchial ACC cases at our institution to identify the optimal therapeutic strategy for this challenging disease. We retrospectively analyzed 11 patients who underwent surgical intervention for tracheobronchial ACC at our institution from 2000 to 2024. Clinical, surgical, and oncologic outcomes were assessed, including the impact of surgical margins and adjuvant therapy. Complete resection was achieved in two cases, while nine patients had positive margins requiring postoperative radiotherapy. No local recurrences were observed, but distant metastases occurred in 54.5% of cases. Oligometastatic disease was effectively managed with local therapy. The 5-year and 10-year overall survival rates were 90% and 75%, respectively. Surgical resection remains the cornerstone of treatment for tracheobronchial ACC, however achieving negative surgical margins is not always feasible. In such cases, postoperative radiotherapy is considered an effective strategy to mitigate the risk of local recurrence. Local treatment of oligometastatic disease may provide a survival. These results indicate the importance of a multimodal treatment approach tailored to the specific challenges of tracheobronchial ACC. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Nagoya University Graduate School of Medicine, School of Medicine |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
|
|
ID登録 |
10.18999/nagjms.88.1.38 |
|
ID登録タイプ |
JaLC |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/874.html |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0027-7622 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2186-3326 |
| 書誌情報 |
en : Nagoya Journal of Medical Science
巻 88,
号 1,
p. 38-48,
発行日 2026-02
|
04_Kawasumi.pdf (755.9 KB)
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